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A PILOT SERIES OF THREE COMPUTER-INTERACTIVE VIDEODISK (CIVD) MODULES WILL BE DEVELOPED FOR TEACHING TOPICS IN TRANSFUSION MEDICINE (TM). THE CONTENT OF THE CIVD MODULES IS DETERMINED FROM THE NHLBI NATIONAL TM CURRICULUM AND INCORPORATES BOTH THE ETHICAL AND PSYCHOSOCIAL ISSUES INVOLVED IN THE PRACTICE OF TM. THE AUDIOVISUAL ELEMENT OF THE CIVD PACKAGES WILL BE SUPPLEMENTED BY APPROPRIATE WRITTEN ...

THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO PRODUCE A PORTABLE, MINIATURIZED DIALYSIS MACHINE WHICH IS SIMPLE, SAFE, AND SYMPTOM-FREE IN OPERATION. THIS DIALYSIS MACHINE SHOULD ALLOW THE AVERAGE HEMO-OR PERITONEAL DIALYSIS PATIENT TO PERFORM DIALYSIS BY HIMSELF AT HOME, UNASSISTED. THE MACHINE WILL BE SMALL (12 LBS.), PORTABLE, AND TOTALLY SELF-CONTAINED (WITHOUT NEED FOR CONNECTION TO WATER SUPP ...

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MEDICAL SCIENCE HAS PROGRESSED TO THE POINT THAT CATHETERS AND ANGIOSCOPES CAN BE USED FOR DIRECT VISUALIZATION OF THE INTERIOR SURFACES OF THE HEART AND CORONARIES. THE PRIMARY HINDRANCE TO FURTHER PROGRESS IN THIS FIELD IS THE LACK OF A MINIATURIZED ANGULATION SYSTEM. THE PROPOSED CONCEPT SUGGESTS THAT PROPRIETARY MATERIALS BE INCORPORATED INTO THE TIP OF A CATHETER OR ANGIOSCOPE TO MAKE THEM MA ...

OPTICAL DESIGN STUDIES WILL BE CARRIED OUT TO DEVISE AN OPTICS MODULE FOR FLOW CYTOMETRY SUCH THAT THE FLOW CHAMBER BECOMES AN INTEGRAL PART OF THE OPTICAL SYSTEM AND FLUOR- ESCENCE IS COLLECTED FOR ALMOST A FULL 4 STERIDIANS (DUAL- HEMISPHERICAL SPACE). AN IMPROVEMENT OF AT LEAST A FACTOR OF FOUR IN THE EFFICIENCY OF LIGHT COLLECTION OVER EXISTING DESIGNS AND BY MORE THAN AN ORDER OF MAGNITUDE OV ...

RECENT INFORMATION SUGGESTS THAT THE MEXICAN HISPANIC POPU- LATION IN THE UNITED STATES IS AT HIGH RISK FOR CORONARY HEART DISEASE, DIABETES MELLITUS, AND SOME SITE-SPECIFIC FORMS OF CANCER. OTHER DATA INDICATE THAT SOCIOCULTURAL FACTORS MAY PLAY A PRIMARY ROLE IN DETERMINING THE HEALTH STATUS OF THIS POPULATION. THE MOST IMPORTANT FACTORS IMPLICATED ARE DIET-RELATED KNOWLEDGE, ATTITUDES, AND BEHA ...

MED INSTITUTE PROPOSES THE DEVELOPMENT AND TESTING OF AN INNOVATIVE PORTABLE CONSTANT-TILT DEFIBRILLATOR WITH AN LCD-ECG MONITOR. THE DESIGN APPROACH IS BASED UPON YEARS OF DEFIBRILLATION RESEARCH THAT HAS RESULTED IN DEFIBRILLATOR DESIGN EQUATIONS FOR OPTIMAL USE OF ENERGY. CONSTANT-TILT CONTROL PROVIDES COMPENSATION FOR HIGH THORACIC IMPEDANCE BYAUTOMATICALLY INCREASING THE DURATION OF THE TRUNC ...

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DIAGNOSIS OF SMALL LIVER TUMORS IS USUALLY DIFFICULT BY CONVENTIONAL X-RAY, EVEN WHEN AIDED BY CT. ADMINISTRATION OF AN INTRAVENOUS CONTRAST AGENT CONSISTING OF EMULSIFIED IODINATED OIL PROVIDES EXCELLENT CONTRASTS OF LIVER TUMORS WITH MINIMAL TOXICITY. THE PRODUCT, HOWEVER, IS MADE IN LABORATORY SCALE USING RELATIVELY UNCHARACTERIZED EMULSIFIERAND SMALL HOMOGENIZING BOTTLES WITH EMPIRICALLY DEFIN ...

WE PROPOSE TO DEVELOP THE APPLICATION OF NEW TWO DIMENSIONAL, STATE OF THE ART CHARGE COUPLED DEVICE (CCD) IMAGE DETECTORS TO THE PROBLEM OF ANALYSIS OF PROTEINS BY DIGITIZATION OF TWO DIMENSIONAL POLYACRYLAMIDE ELECTROPHORETIC GELS. LONG TERM SUCCESS OF THIS PROJECT WILL RESULT IN COMMERCIALIZATION OF A NEW PRODUCT LINE OF MEDICAL MACHINERY, MORE WIDESPREAD USE OF ELECTROPHORESIS IN A CLINICAL SE ...