Award Data

STRIATAL TRANSPLANTATION OF NEUROTRANSMITTER CELLS, IMMUNOISOLATED WITHIN A PERMSELECTIVE POLYMER MEMBRANE CAPSULE, REPRESENTS A NOVEL APPROACH TO THE TREATMENT OF PARKINSON'S DISEASE. THE TECHNIQUE HAS HAD PROMISING RESULTS IN SEVERAL RODENT MODELS, AND PRIMATE STUDIES ARE UNDERWAY. THE OVERALL OBJECTIVE OF THIS RESEARCH IS TO COMPLETE THE DEVELOPMENTS NECESSARY FOR WIDESPREAD MEDICAL ACCEPTANCE ...

THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS THE DEVELOPMENT AND INTRODUCTION TO MEDICAL PRACTICE OF AN EFFECTIVE BIOCOMPATIBLE IMPLANTABLE HYBRID ARTIFICIAL ENDOCRINE PANCREAS THAT IS CAPABLE OF SIGNIFICANT IMPROVEMENT IN THE THERAPY OF INSULIN-DEPENDENT DIABETES. THE SPECIFIC AIM OF THIS PROJECT IS TO EXTEND AND MODIFY A PROCESS FOR CELLULAR ENCAPSULATION TO THE ISLETS OF LANGERHANS, USING A CO-E ...

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THE BUSINESS OF AQUACULTURE HAS INCREASED SUBSTANTIALLY IN THE UNITED STATES IN RECENT YEARS. THE USE OF INTENSIVE AQUACULTURE TECHNIQUES IN THE U.S. HAS PLACED AN INCREASING EMPHASIS ON MAINTAINING WATER QUALITY. DEVELOPMENT OF A LOW-COST AND RELIABLE AUTOMATED WATER QUALITY AND FEED CONDITION MONITORING AND CONTROL SYSTEM WOULD PROVIDE BOTH RESEARCH AND COMMERCIAL AQUACULTURISTS WITH A MEANS OF ...

THIS PROPOSAL IDENTIFIES A STRATEGY, BASED ON NEW OFF-THE-SHELF TOOLS, PROTOTYPING, AND INTERACTION WITH MAINTENANCE PERSONNEL, FOR DEVELOPING INFORMATION PRESENTATION GUIDELINES WHICH SUPPORT MAINTENANCE PERSONNEL WITH VARIOUS EXPERIENCE LEVELS, THE ENVIRONMENTS IN WHICH THE MAINTENANCE IS PERFORMED, THE DIFFERENT MEDIA AVAILABLE FOR ONLINE INFORMATION DISPLAY, AND THE COST-EFFECTIVE OF IMPLEMENT ...

KVH INDUSTRIES PROPOSES TO THOROUGHLY INVESTIGATE BOTH CONVENTIONAL AND INNOVATIVE USES FOR THE SELF POWERED VEHICLE DETECTOR (SPVD) AND TO MODIFY THE EXISTING DESIGN, IF REQUIRED, TO MEET THE SPECIFICATIONS OF THE NEW APPLICATIONS. THE OVERALL GOAL OF THE PROPOSED SBIR PHASE IEFFORT CAN BE SUBDIVIDED INTO THREE FUNDAMENTAL OBJECTIVES: RESEARCH INTO THE VARIOUS APPLICATIONS OF SPVD TECHNOLOGY AND ...

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THE HOSTILE ENVIRONMENT EXISTING AT THE BORE SURFACE OF GUN BARRELS USED IN HIGH RATE OF FIRE AIRCRAFT CANNONS PRESENTS A FORMIDABLE DESIGN CHALLENGE TO THE GUN DESIGNER. HEAT, FRICTION, CORROSION AND WEAR AT THE BORE SURFACE ACT IN UNISON TO RAPIDLY DETERIORATE THE BORE. CHROME PLATING IS PRESENTLY THE ONLY COST EFFECTIVE METHOD OF IMPROVING BORE SURFACE LIFE. PLASMA SURFACE ALLOYING IS AN EMERGI ...

PHASE I AIMS TO DEMONSTRATE THE FEASIBILITY OF FABRICATING PREFORMS FOR CERAMIC COMPOSITE SHAPES OF INTEREST TO FOSSIL ENERGY BY USING PROPRIETARY THREE-DIMENSIONAL BRAIDING TECHNOLOGY. HIGH PERFORMANCE CERAMIC COMPOSITES, OPERATING IN EXTREME CONDITIONS OF TEMPERATURE AND CORROSIVE ENVIRONMENT, REQUIRE PREFORM ARCHITECTURES THAT CAN PROVIDE TOUGHNESS, STRENGTH, AND A CAPACITY TO ELIMINATE FAILURE ...

THIS RESEARCH IS DIRECTED TOWARD IMPROVEMENT OF PRESENT SELF CALIBRATING, THERMOPILE BASED, CAVITY RADIOMETERS FOR USE IN RADIANCE MEASUREMENTS FROM EARTH VIEWING SATELLITE INSTRUMENTS. THE PRIMARY THRUST IS TO IMPROVE THE RESPONSIVITY OF THE DEVICE, AND MINIMIZE POSSIBLE THERMAL OFFSET SIGNALS WITHIN THE SENSOR. THE APPROACH INVOLVES REDESIGN OF THE THERMAL IMPEDANCE OF THE THERMOPILE ELEMENT AND ...