Award Data

BIODE will utilize the results of its Phase I research to develop (Phase II) and commercialize (Phase III) a totally new solid state biosensor technology for biological measurements. This technology is based upon the merging of two technologies: Triple Helix Nucleic Acid Probes with Acoustic Plate Mode (APM) micro sensors. Recent advances by BIODE in the design and operation of APM devices have re ...

An investigation of nickel coating processes to provide corrosion protection for 6061-T6 aluminum alloy in a marine environment is proposed. The effects of aluminum preparation and pretreatment steps will be investigated. Additionally, strategies which utilize multiple layers of nickel of different compositions will also be explored.

A new and novel apparatus, the High Aspect Rotating-Wall Vessel (HARV), developed by NASA at the Johnson Space Center, Houston, TX, produces three dimensional cellular aggregates (spheroids) under low fluid shear conditions, an aspect of simulated microgravity. The vessel rotates cells and culture medium in a disk-shaped chamber about a horizontal axis with zero headspace. Adequate gas exchange is ...

CytoDiagnostics, Inc., and the University of Oklahoma developed partially automated, user-interactive systems for quantitation of biomarkers used in the diagnosis of bladder cancer. The goal of Phase I is to demonstrate the feasibility of further automation with an online neural network system integrated with the quantitative fluorescence image analysis system to classify bladder cancer cells by t ...

A novel apparatus, the High Aspect Rotating-Wall Vessel (HARV), developed by NASA at the Johnson Space Center, Houston, TX, produces three dimensional cellular aggregates (spheroids) under low fluid shear conditions, an aspect of simulated microgravity. The vessel rotates cells and culture medium in a disk-shaped chamber about a horizontal axis with zero headspace. Adequate gas exchange is maintai ...

DETECTION AND MEASUREMENT OF SOOT IN THE EXHAUST OF TURBINE ENGINES IS IMPORTANT FROM A TACTICAL STANDPOINT OF AIRCRAFT VULNERABILITY. EXIS TING OPTICAL DETECTION METHODS ARE SUBJECT TO ERROR AND SUBJECTIVE ANA LYSIS. A NOVEL SOOT DETECTION METHOD IS PROPOSED FOR DEVELOPMENT. IT RELIES ON THE ELECTROMAGNETIC ENERGY RADIATED BY IONS EMBEDDED IN SOO T PARTICLES. THE FREQUENCY OF THE RADIATION IS VER ...

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A PHASE I FEASIBILITY STUDY IS PROPOSED FOR THE DEVELOPMENT OF A 2400 DEGREE KELVIN GAS SAMPLE CELL WHICH IS CAPABLE OF SIMULATING THE COMBU STION PRODUCTS OF HYDROGEN-AIR SCRAMJET PROPULSION SYSTEM AT PRESURES FROM 0.5 TO 2.0 ATMOSPHERES, FLOWS FROM 0 TO 1.0 STANDARD LITERS PERMI NUTE, AND A CELL COMPOSITION OF AIR WITH 20 PERCENT WATER VAPOR BY WEI GHT. ADDRESSED WITHIN THE PROPOSAL IS THE PRIMA ...

FIBER MATERIALS, INC. (FMI) PROPOSES A PROGRAM TO DEVELOP A NEW CLASS OF SMART MATERIALS WHICH HAVE THE CAPABILITY OF SENSING ENVIRONMENTAL CHANGE AND RESPONDING TO IT IN A DESIRED MANNER. PIEZOELECTRIC SENSORS AND ACTUATORS WILL BE COUPLED ELECTRICALLY TO FORM THE SMART MATERIAL STRUCTURE. A NEW TYPE OF COMPOSITE MATERIAL CONTAINING PIEZOELECTRIC TUBES WILL BE DEVELOPED FOR HIGH ACTUATION WITH LO ...

High surface area, super adsorbent activated carbon fibers are potentially an excellent adsorptive material for chemical protective uniforms. However, these fibers are not currently available from a domestic source. A Phase I program is proposed to demonstrate the feasibility of producing laboratory scale quantities of short highly activated carbon fibers based on a U.S. developed process (U.S. Pa ...