Award Data

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

Technological advances have facilitated weapons systems capable of simultaneously supporting multiple missions leading to cost efficiencies and greater operational flexibility.Future systems capable of deploying multiple payloads from a single missile will enable various targets to be attacked with a single launch allowing more efficient use of limited and valuable resources.For such a system to w ...

Modeling and simulation on high-end computing systems has grown increasingly complex in recent years as both models and computer systems continue to advance. The majority of coding and debugging time is not spent defining the problem physics but instead in balancing computations between multiple heterogeneous devices, handling communication of data, managing distributed memory systems, and providi ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will be the discovery of new ionization technology for use with mass spectrometry. This technology will enable lower cost, lower energy use, and reduced user expertise, which may potentially drive mass spectrometry into large and underserved markets such as medical diagnostics and field porta ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is in bringing epoxy based conductive polymer anticorrosion paint system to the market. Corrosion will cost the US economy over $1 trillion in 2015. It is highly desirable to develop more effective anticorrosion technologies to reduce this huge economic cost of corrosion. The most effective a ...

ABSTRACT:A system is proposed to access, collate and process imagery from multiple small satellite constellations. The imagery is fused and registered to a common reference so that exploitation algorithms, such as change detection and event monitoring, are reported with accurate geographic coordinates. The system, called SatTel, is implemented as open source software that is designed to run on the ...

DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

Project Summary As United States healthcare seeks to address inconsistent quality and overwhelming cost data and technology have become central to all suggested approaches With newly available electronic health data and massive growth in processing power the hardest challenges in using clinical data are becoming clear Big data holds the potential to enable personalized patient care population ...