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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. he 3D Platelet Bank: A Clinical-grade, Scalable, 3D Microbioreactor Bone Marrow Mimetic for Platelet Production

    SBC: KIYATEC, INC.            Topic: NIBIB

    Project Summary Abstract The transfusion of platelets is a major component of the treatment of cancer patients undergoing chemotherapy and or bone marrow transplants trauma patients sepsis and battlefield injuries However due to a complete reliance upon donors as the only current approved source of platelets and the strict short shelf life and storage conditions of donor derived platelets ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Polo-box PLK1 Inhibitors Target Tumors Resistant to ATP Competitive Compounds

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    Polo like kinase PLK is a central player in regulating entry into and progression through mitosis Many studies have validated PLK as an anti tumor drug target and its inhibition is potently anti proliferative to cancer cells However recent data suggests that there are two major disadvantages of the conventional approach to blocking the kinase activity of PLK First both general kinome ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. STTR Phase I: Marine Antifouling Deterrent Coatings for Quantum Paints

    SBC: ENGINEERED MARINE COATINGS, INC.            Topic: MI

    This Small Business Innovation Research Phase I project will develop an environmentally benign yet highly effective marine antifouling coating for the American yacht market. The coating is a non-biocidal, foul release surface which does not require the vessel to move to obtain antifouling protection. It is a non-ablative multi-modal coating that will deter settling marine larvae when the vessel is ...

    STTR Phase I 2017 National Science Foundation
  4. Membranes and Materials for Energy Efficiency; Subtopic c Title: Development of Corrosion Resistant Carbon Support for Ultra-low PGM Catalysts

    SBC: Greenway Energy LLC            Topic: 15c

    Carbon is used as a support material for both anode and cathode catalysts in state-of-the-art polymer electrolyte membrane (PEM) fuel cells. Carbon support is susceptible to corrosion under the cathode operating conditions such as presence of oxygen and water, low pH, and high potential at the cathode interface. Corrosion of state-of-the-art carbon supports is inevitable, which leads to platinum c ...

    SBIR Phase I 2017 Department of Energy
  5. New Approaches to Improved PEM Electrolyzer Ion Exchange Membranes

    SBC: Tetramer Technologies, L.L.C.            Topic: 13a

    This technology will significantly lower the energy cost for production of industrial gases, transportation fuels, and renewable energy and will aid in securing the US microgrid through improved backup power energy. This knowledge based commercial enterprise will not only create > 100 high paying jobs that will stay in the US, but also demonstrate expanded American leadership in high technology pr ...

    SBIR Phase II 2017 Department of Energy
  6. Membranes and Materials for Energy Efficiency – Metal Hydride Materials for Compression Metal hydride material development for high efficiency and low cost hydrogen compressors

    SBC: Greenway Energy LLC            Topic: 15d

    To make the hydrogen economy realistic at a large scale, one of main technical issues to be overcome is relative to the high pressure hydrogen delivery. Traditional hydrogen compressors suffer from high operating and maintenance costs and high capital investment. Metal hydride based compressors represent a realistic alternative that can potentially overcome all of the technical hurdles of the trad ...

    SBIR Phase I 2017 Department of Energy
  7. Rational Design of sub-100 nm Polystyrene Particles With a Low Coefficient of Variation in Size

    SBC: Tetramer Technologies, LLC            Topic: N/A

    In this Phase I SBIR program, Tetramer Technologies will develop new, commercially attractive, highly monodisperse polystyrene latex standards in a variety of sizes (i.e. 30 nm to 100 nm) via emulsion polymerization processes that employ a surfactant and that are surfactant-free. Surfactant free emulsions will be stabilized through the use of ionic comonomers in the emulsion polymerization. The fo ...

    SBIR Phase I 2017 Department of CommerceNational Institute of Standards and Technology
  8. A Novel Scaffold to Promote Skin Regeneration

    SBC: FIRSTSTRING RESEARCH, INC.            Topic: NIAMS

    PROJECT SUMMARY Dermal scarring affects more than million people worldwide annually over million people are injured in motor vehicle accidents over million patients are severely burned and thousands of warriors are wounded in military blasts In severe burns more than of patients develop hypertrophic scar contraction which leads to hypertrophic scar contractures HSc HSc a ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Millimeter-wave (mmw) DNP/EPR Front-end Compatible with Versatile High-field NMR Probes

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    A Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes Abstract There has been explosive growth in interest in Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS over the past five years because it has demonstrated S N gains exceeding two orders of magnitude at K compared to conventional MAS NMR and non spinning NMR of biological macro ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Ice Free Vitrification and nanowarming of large cartilage samples for transplantation

    SBC: TISSUE TESTING TECHNOLOGIES, LLC            Topic: NIAMS

    Resurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis induced articular cartilage surface damage Chondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantation We have previously developed an ice free vitrification me ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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