Award Data

Abstract: “sHLA Protein Chip” The class I [A, B, C] and class II HLA proteins [DRB1, DQ, DP] comprise the heart of the inducible human immune system. For organ, marrow and stem cell transplantation, the development of serum-born antibodies against one or more of those many HLA proteins comprises the best and earliest test for transplant rejection. Because of the enormous medical importance of ...

Our service members deployed worldwide are at risk of exposures to local environmental and industrial toxicants which can potentially result in long-term adverse health effects. Understanding the impact of these exposures is critical for improved force protection and safeguarding individual soldier health. Capturing and classifying exposure data is essential for developing and implementing risk mi ...

For dynamic protection of LWIR sensors from laser dazzler threats, Nanohmics, Inc., proposes to develop a thin, light-weight, electronically tunable notch filter based on microfabricated graphene-integrated metasurfaces. The optical filter can reject a specific narrow spectral line (“notch”) or multiple simultaneous notches. The metasurface comprises an engineered array of resonant microstruct ...

The goal of the Phase II program is to demonstrate growth of large-area single-crystal diamond substrates having surface area of 6 cm2 and suitable for electronic device applications. This will represent a major leap in available substrate area, from less than 1 cm2 available today. The technical path will directly follow the work begun in the Phase I program, which is, using our toroidal plasma C ...

Systems & Processes Engineering Corporation (SPEC) is proposing a fast moving Phase II Expendable Active RF Technologies for Helicopters (EARTH) program to deliver a fully functional 1”x2”x8” active expendable RF countermeasures prototype flight unit, which is form/fit compatible with the AN/ALE-47 dispenser. The proposed countermeasures flight unit (microUAV) expendables are configured with ...

Proposal title: Resilient Wayside Structures to Reduce Severity of Passenger Equipment Collisions and Derailments Additional passenger fatalities/injuries can occur during derailments involving interaction with wayside structures. Analogously, automobile fatalities often result from interaction of vehicles with roadside structures; personnel hazard reduction is a key design criterion for roadsid ...

The parasitic tapeworm Taenia solium causes two diseasestaeniasisadult worm in the intestineand cysticercosistissue infection by the cystwhich can lead to seizuresThe Tsolium life cycle involves both humans and pigshowever humans are the only definitive host for the adult Tsolium tapewormDiagnosing people infected with the adult worm is a critical step toward eliminating Tsolium althogetherHowever ...

A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

The longterm objective of the Litmus Health platform is to allow researchers and clinicians to use data on cancer patients from wearables/sensors and smartphones. Collecting real-time, high-quality data from patients will transform care and clinical trials. Automating data collection, storage, analysis, and interpretation of data will result in better measurement of signs and symptoms and improved ...

The preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunotherapies, is evolving from the traditional use of mouse models to the use of other animal models including canine, rat, and minipig. Each of these non-mouse models carries its own advantages and abilities to increase the clinical relevance of the model as compared to mouse models. Yet, the wid ...