Award Data

The physiological health of soldiers is at risk due to potential biological agent exposure. Many of these agents are protein-based and can cause alterations in cellular proteins. The ability to rapidly monitor, detect, and analyze proteins will enable earlier identification of exposure and result in quicker intervention potentially saving many lives. A key step in analysis of protein mixtures is p ...

The proposed Phase II SBIR program is dedicated to the creation and testing of a multispecific DNA biowarfare sensor based on ultrathin oligonucleotide-modified conducting polymer films. Based on the reagent-free sensor prototype developed in Phase I, wh

We propose to build in Phase II a compact, rugged laser photoacoustic spectrometric (L-PAS) prototype sensor system (at technology readiness level TRL-6) for continuous, real-time broadband analysis of multiple chemicals. It will incorporate a tunable infrared quantum cascade laser (QCL), photoacoustic cell and air sampler system in a sealed decontamination-capable module and an efficient algorith ...

Nerve agents (NA) such as sarin, soman, tabun or VX are organophosphate compounds similar to those used as pesticides but with much higher toxicity that can cause death within minutes. Use of NA weapons of mass destruction has become a real threat since the Iraq–Iran war in the 1980s and the sarin attacks against civilians in Japan in 1994 and 1995. Nerve agents are relatively simple and inexpen ...

Intelligent Automation Inc., (IAI) presents a novel reliable, miniature, unobtrusive light weight Accurate Real-time Methyl Salicylate Sensing System (ARMSSS) for testing effectiveness of chemical suits. The ARMSSS collects real-time data and accurately identifies chemical break-through sites in Man-in-Stimulant Testing, where Methyl Salicylate (MeS) is used as the simulant for chemical agents. T ...

During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

First responders play very important roles in the protection of people and their properties, as well as in homeland security and national defense. Various kinds of protective suits, masks, gloves and boots are available for use as protection from the various hazardous conditions they may face. A GC/MS based method, ASTM F739-07, is commonly used to determine the duration during which a protectiv ...

A miniature, transportable filter system is required for warfighters when traditional resupply is unavailable. The desired technology would remove both chemical and biological agents. A device that integrates sensing capability to actuate the purification system is also desired. We developed a non-woven filter using a nano alumina fiber only 2 nanometers in diameter. It is capable of > 99.9999 ...

This SBIR project, by utilizing the principle of Fluctuation-Enhanced Sensing (FES), aims to explore the potential of enhancing the sensitivity and selectivity of electrostatic bacterium spore analyzers, specifically Ion Mobility Spectrometers (IMS) and Mass Spectrometers (MS). We propose a high performance framework that incorporates FES to enhance the detection and classification of bio-aerosols ...

The project proposed here will develop a polymer based pre-concentrator integrated with a novel membrane inlet for a mass spectrometer. By using an integrated solution, the dead volume of the pre-concentrator can be minimized, thus increasing the pre-concentration gain (projected to be > 17000 with gas flows of 1 l/min containing analyte to 40 pg/l) well beyond that of solid sorbent tubes. Also, t ...