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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System

    SBC: Lynntech Inc.            Topic: CBD08101

    The physiological health of soldiers is at risk due to potential biological agent exposure. Many of these agents are protein-based and can cause alterations in cellular proteins. The ability to rapidly monitor, detect, and analyze proteins will enable earlier identification of exposure and result in quicker intervention potentially saving many lives. A key step in analysis of protein mixtures is p ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  2. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: SCIENCE & ENGINEERING SERVICES, INC.            Topic: CBD08104

    We propose to build in Phase II a compact, rugged laser photoacoustic spectrometric (L-PAS) prototype sensor system (at technology readiness level TRL-6) for continuous, real-time broadband analysis of multiple chemicals. It will incorporate a tunable infrared quantum cascade laser (QCL), photoacoustic cell and air sampler system in a sealed decontamination-capable module and an efficient algorith ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  3. Aptamer Enhanced Biorecognition Reagent System

    SBC: OMNISITE BIODIAGNOSTICS, INC.            Topic: N/A

    OmniSite proposes to continue Phase I effort to develop aptamer-based assays to anthrax spores and SEB for detection instruments based on ECL, FP, and FRET formats. OmniSite will compare the different assay formats to determine which of thesedemonstrates the most sensitivity and specificity, as well as being robust, cost effective, and facile. Performance characteristics of the most sensitive ...

    SBIR Phase II 2003 Department of DefenseOffice for Chemical and Biological Defense
  4. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Nerve agents (NA) such as sarin, soman, tabun or VX are organophosphate compounds similar to those used as pesticides but with much higher toxicity that can cause death within minutes. Use of NA weapons of mass destruction has become a real threat since the Iraq–Iran war in the 1980s and the sarin attacks against civilians in Japan in 1994 and 1995. Nerve agents are relatively simple and inexpen ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  5. A Novel Approach for Spectral Unmixing and Classification of Chemical and Biological Agents

    SBC: Intelligent Automation, Inc.            Topic: N/A

    Besides performing a thorough statistical analysis of the government furnished data sets to determine the features and metrics for spectral unmixing, Intelligent Automation, Inc. and Prof. C. Chang of University of Maryland at Baltimore County also proposean innovative approach to detect and classify chemical and biological agents. There are two major steps. First, we propose to apply a recently d ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  6. Accurate Real-time Methyl Salicylate Sensing System (ARMSSS)

    SBC: Intelligent Automation, Inc.            Topic: CBD09103

    Intelligent Automation Inc., (IAI) presents a novel reliable, miniature, unobtrusive light weight Accurate Real-time Methyl Salicylate Sensing System (ARMSSS) for testing effectiveness of chemical suits. The ARMSSS collects real-time data and accurately identifies chemical break-through sites in Man-in-Stimulant Testing, where Methyl Salicylate (MeS) is used as the simulant for chemical agents. T ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  7. Portable System for Sample Preparation and Differentiation of Pathogens at Strain Level

    SBC: Lynntech Inc.            Topic: CBD04107

    During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
  8. RNAi screening for Identification of Compounds to Induce Suspended Animation or Hypometabolism

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    While the phenomenon of suspended animation has not been widely studied in humans, there are many anecdotal and medically verified examples of humans being in a state that is comparable to suspended animation when they have been accidentally nearly frozenfor short periods of time. There could be many advantages to inducing suspended animation or hypometabolism in humans such as extending survival ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  9. Polyoxometalate Nanoparticles as Reversible and Selective Surface Contamination Monitors

    SBC: Lynntech Inc.            Topic: N/A

    The threat of chemical warfare agents used against our military is as great as it ever has been. The U.S. Naval forces present large targets for terrorist type activities at all parts of the globe. There are many types of quick detection strategies, suchas M8/M9 paper and Chemical Agent Monitors, which can screen liquid and powder forms of chemical agent dispersal, respectively. However, the ne ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  10. Rapid Air/Vapor Sampling System for Chemical Threats

    SBC: Lynntech Inc.            Topic: CBD09106

    First responders play very important roles in the protection of people and their properties, as well as in homeland security and national defense. Various kinds of protective suits, masks, gloves and boots are available for use as protection from the various hazardous conditions they may face. A GC/MS based method, ASTM F739-07, is commonly used to determine the duration during which a protectiv ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense

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