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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System

    SBC: LYNNTECH INC.            Topic: CBD08101

    The physiological health of soldiers is at risk due to potential biological agent exposure. Many of these agents are protein-based and can cause alterations in cellular proteins. The ability to rapidly monitor, detect, and analyze proteins will enable earlier identification of exposure and result in quicker intervention potentially saving many lives. A key step in analysis of protein mixtures is p ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  2. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: SCIENCE & ENGINEERING SERVICES, INC.            Topic: CBD08104

    We propose to build in Phase II a compact, rugged laser photoacoustic spectrometric (L-PAS) prototype sensor system (at technology readiness level TRL-6) for continuous, real-time broadband analysis of multiple chemicals. It will incorporate a tunable infrared quantum cascade laser (QCL), photoacoustic cell and air sampler system in a sealed decontamination-capable module and an efficient algorith ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  3. Accurate Real-time Methyl Salicylate Sensing System (ARMSSS)

    SBC: Intelligent Automation, Inc.            Topic: CBD09103

    Intelligent Automation Inc., proposed phase II approach and the demonstrated phase I prototype aims in the development of high sensitivity and selectivity for real time detection of Methyl Salicylate (MeS). In the phase I effort we demonstrated successfully: (1) Quartz Crystal Microbalance sensors for detection of MeS, (2) real time detection of change in concentration of MeS, (3) reuse of the Me ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. Integrated Automated Pre-concentrator Inlet for Mass Spectrometer

    SBC: 1st Detect Corp            Topic: CBD09106

    This proposal describes a project to develop a pre-concentrator inlet system for a mass spectrometer. The pre-concentrator utilizes a heated mesh design that is coated with a variety of sorbent materials to provide high pre-concentration with adversely affecting the analysis time. An innovative method of evacuating the pre-concentrator chamber provides an additional gain in pre-concentration of 2 ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Aptamer Enhanced Biorecognition Reagent System

    SBC: OMNISITE BIODIAGNOSTICS, INC.            Topic: N/A

    OmniSite proposes to continue Phase I effort to develop aptamer-based assays to anthrax spores and SEB for detection instruments based on ECL, FP, and FRET formats. OmniSite will compare the different assay formats to determine which of thesedemonstrates the most sensitivity and specificity, as well as being robust, cost effective, and facile. Performance characteristics of the most sensitive ...

    SBIR Phase II 2003 Department of DefenseOffice for Chemical and Biological Defense
  6. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Nerve agents (NA) such as sarin, soman, tabun or VX are organophosphate compounds similar to those used as pesticides but with much higher toxicity that can cause death within minutes. Use of NA weapons of mass destruction has become a real threat since the Iraq–Iran war in the 1980s and the sarin attacks against civilians in Japan in 1994 and 1995. Nerve agents are relatively simple and inexpen ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  7. No Power Detection and Identification of Nerve Agents

    SBC: LYNNTECH INC.            Topic: CBD10101

    Rapid identification of asymmetric warfare modes, including unconventional chemical agents based attacks, is vital to the protection of U.S. armed forces personnel. Existing detection methods use bulky and expensive laboratory equipment to analytically determine the identity and concentration of chemical threats, negating their battlefield use. Colorimetric indicators such as the currently deploye ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. A Novel Approach for Spectral Unmixing and Classification of Chemical and Biological Agents

    SBC: Intelligent Automation, Inc.            Topic: N/A

    Besides performing a thorough statistical analysis of the government furnished data sets to determine the features and metrics for spectral unmixing, Intelligent Automation, Inc. and Prof. C. Chang of University of Maryland at Baltimore County also proposean innovative approach to detect and classify chemical and biological agents. There are two major steps. First, we propose to apply a recently d ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  9. Accurate Real-time Methyl Salicylate Sensing System (ARMSSS)

    SBC: Intelligent Automation, Inc.            Topic: CBD09103

    Intelligent Automation Inc., (IAI) presents a novel reliable, miniature, unobtrusive light weight Accurate Real-time Methyl Salicylate Sensing System (ARMSSS) for testing effectiveness of chemical suits. The ARMSSS collects real-time data and accurately identifies chemical break-through sites in Man-in-Stimulant Testing, where Methyl Salicylate (MeS) is used as the simulant for chemical agents. T ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  10. Portable System for Sample Preparation and Differentiation of Pathogens at Strain Level

    SBC: LYNNTECH INC.            Topic: CBD04107

    During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
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