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TODAY AN OVERWHELMING MAJORITY OF CFD CALCULATIONS ARE DONE WITH STANDARD FIXED GRID FINITE DIFFERENCE METHODS. HOWEVER, A SIMPLE CALCULATION CAN ESTABLISH THAT SUCH METHODS CANNOT POSSIBLY EXPLOIT THE FULL COMPUTING POWER OF TODAY'S COMPUTING EQUIPMENT NOR CAN THEY DELIVER HIGHLY ACCURATE SIMULATIONS OF FINE SCALE FLOW PHENOMENA IN COMPLEXFLOW DOMAINS. TO FULLY EXPLOIT CONTEMPORARY COMPUTING CAPA ...

THIS PROJECT INVOLVES ANALYSIS AND DESIGN OF SEVERAL CONFIGURATIONS FOR PASSIVE AIRBLAST VALVES TO STRONGLY ATTENUATE BLAST FROM CONVENTIONAL WEAPONS. DESIGN GOALS ARE ATTENUATION OF INCIDENT BLAST OVERPRESSURES BY AT LEAST TWO ORDERS OF MAGNITUDE, WHILE OFFERING NO MORE RESTRICTION TO NORMAL AIRFLOW THAN EXISTING ACTIVE BLAST VALVES. WE PROPOSE TO BASE OUR DESIGNS ON VENTED PANEL CONFIGURATIONS W ...

THE U.S. AIR FORCE AND OTHER DEFENSE ELEMENTS HAVE RECOGNIZED THE NEED TO SOLVE THE PROBLEM OF LACK OF SURVIVABILITY OF CURRENT AIR TRAFFIC MANAGEMENT CAPABILITIES IN A TACTICAL ENVIRONMENT. AS PART OF THE TRANS-CENTURY SOLUTION TO THIS PROBLEM, THE DEVELOPMENT OF THE AUTOMATED TACTICAL LAUNCH AND RECOVERY SYSTEM (ATALARS) MUST INTEGRATE EMERGING AUTOMATION CAPABILITIES AND DISPLAY TECHNOLOGIES IN ...

THE MAIN OBJECTIVE OF THIS PHASE I PROJECT WAS TO ESTABLISH A SOURCE OF SERUM-FREE MEDIUM SUITABLE FOR SUSTAINED GROWTH OF EARLY PASSAGE SYRIAN HAMSTER EMBRYO (SHE) CELLS. SPECIFIC AIMS INCLUDED SELECTION OF A BASAL MEDIUM SUPPORTIVE OF CLONAL GROWTH IN LIMITING SERUM CONCENTRATIONS, REPLACEMENT OF SERUM BY SELECTED GROWTH FACTORS AND HORMONES, OPTIMIZATION OF SUPPLEMENTS BY CLONAL TITRATIONS, AND ...

THE PURPOSE OF THIS RESEARCH IS TO FABRICATE AND TEST THE EFFICACY OF CULTURE DISHES WITH UNIQUE SURFACES. THIN FILMSOF METAL, METAL ALLOYS AND CERAMICS WILL BE APPLIED TO STANDARD POLYSTYRENE CULTURE DISHES. GROWTH OF FIBROBLAST AND OSTEOBLAST CELL LINES ON THE CULTURE PLATES WILL SERVE AS MODELS OF SOFT TISSUE AND HARD TISSUE MAMMALIAN CELLS. CELL MORPHOLOGY AND GROWTH WILL BE MONITORED BY PHASE ...

TO DEMONSTRATE THAT CULTURED MAMMALIAN CELLS CAN BE FROZEN, DRIED, REHYDRATED, AND REVIVIFIED, FOUR CELL LINES WERE CHOSEN FOR EXPERIMENTS THAT WILL DETERMINE: (1) THE OPTIMUM METHOD OF CELL VITRIFICATION (FREEZING WITHOUT ICE CRYSTALS)AND WHETHER CRYOPROTECTION IS NECESSARY, (2) WHETHER DRYING PROTECTION IS NEEDED, (3) HOW TO MAKE DRYING COMPATIBLE WITHTHE NATURE OF THE CELL, (4) WHETHER UNIFORMI ...

THE OBJECTIVES OF THIS PROJECT ARE TO ESTABLISH A REGISTER OF INHERITED METABOLIC DISEASES (IMD'S) THAT WILL PROVIDE DATA FOR APPROPRIATE HEALTH-CARE PROVIDERS TO IDENTIFY, CLASSIFY, AND TRACK PATIENTS WITH IMD'S. THE METHODOLOGY DEVELOPED TO IMPLEMENT AS ACCURATE AND COMPLETE REGISTER INFORMATION AS POSSIBLE ON TWO IMD'S (GALACTOSEMIA AND MSUD)WILL BE TRANSFERRABLE TO OTHER DISEASES. TASKS INCLUD ...

UNTIL NOW, THE BENEFITS OF COMPUTERIZATION HAVE NOT SPREAD TO IMAGE-BASED FIELDS SUCH AS PATHOLOGY. ALTHOUGH A FEW EXPENSIVE IMAGE-PROCESSING COMPUTER SYSTEMS HAVE BEEN USED FOR PATHOLOGY RESEARCH, AFFORDABLE, GENERAL-PURPOSE SYSTEMS HAVE BEEN UNAVAILABLE. IMAGE PROCESSING HAS BEEN LIMITED TO BLACK-AND-WHITE IMAGES. RECENT PROGRESS IN MICROCOMPUTERIMAGE-PROCESSING HARDWARE WILL NOW ALLOW THE PRODU ...

THE GEOMETRIC INCREASE IN THE NUMBER OF INDIVIDUALS INFECTED BY HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) HAS CREATED SERIOUS SOCIAL, ECONOMICAL AND LIFE-THREATENING ISSUES TO THE HUMAN RACE. IT IS OF PRESSING CONCERNS TO DEVELOP EFFECTIVE MEASURES FOR CONTROLLING THE SPREAD OF THIS DISEASE, FAVORABLY BY INDUCING ACTIVE IMMUNITY TO THE INDIVIDUALS AT RISK TO THE INFECTION. BASED ON THE PHENOMENA ...