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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: In-line sensor for monitoring monoclonal antibody production based on hydrogels containing peptide aptamers

    SBC: Applied Biosensors, LLC            Topic: BM

    This SBIR Phase I project will benefit society by reducing the cost of manufacturing biologic pharmaceuticals and improving their quality, including pharmaceuticals that are currently too costly to manufacture because they target relatively small patient populations. The proposed innovation will advance state-of-the-art by providing a continuous in-situ multi-analyte sensor enabling novel methods ...

    SBIR Phase I 2017 National Science Foundation
  2. STTR Phase I: Nondestructive high-resolution measurement of semiconductor carrier density

    SBC: NewPath Research L.L.C.            Topic: MI

    This Small Business Technology Transfer Phase I project will develop advanced tools for semiconductor metrology that are essential for high accuracy at finer resolution as progress continues to the finer lithography nodes. This progress is essential to satisfy the demand for greater performance in numerous consumer products as well as many other applications. The intellectual merit of this project ...

    STTR Phase I 2017 National Science Foundation
  3. High-throughput, multiplexed characterization and modeling of antibody:antigen binding, with application to HSV

    SBC: WASATCH MICROFLUIDICS            Topic: NIAID

    Abstract All therapeutic antibodies and most vaccines critically depend on the ability of antibodies to specifically recognize particular antigens consequently detailed characterization of antibody antigen binding can provide invaluable information to understand and guide development Unfortunately due to the time and expense required atomic resolution structure determination is typically use ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a DNA Aptamer-Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials

    SBC: APOLLODX, LLC            Topic: NIDA

    Development of a DNA Aptamer Based Electrochemical Assay for Acetazolamide in Urine Using a Handheld Biosensor for Compliance Validation in Clinical Drug Trials Thirty to over eighty percent of patients enrolled in pharmaceutical clinical trials do not comply with trial protocols by discarding the drug under investigation or not using the proper dosages This common practice compromises the medica ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Decentralized Key Management using Blockchain

    SBC: Evernym Inc.            Topic: H-SB016.1-002

    The purpose of this SBIR Proposal is to conduct the research needed to enable blockchain technology to serve as serve as a decentralized foundation for privacy-respecting identity management. In this phase, Evernym will research and develop a decentralized key management system (DKMS) based on the DID (Decentralized Identifier) specification developed in Phase I. The DID specification has already ...

    SBIR Phase II 2017 Department of Homeland Security
  6. Tessa Sleep Quality Monitoring

    SBC: EPITEL, INC.            Topic: NHLBI

    ABSTRACT TessaTM is validated medical device wearable capable of providing clinical sleep quality metrics for multiple nights to assess the efficacy of a sleep disorder treatment Tessa records the forehead EEG to stage sleep in an automated report that tracks changes in sleep architecture before and after a treatment for many sleep disorders such as obstructive sleep apnea and insomnia There is ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Stream Dx: accurate and efficient, point-of-care uroflometry for improved diagnosis, monitoring, and post-treatment evaluation of LUTS

    SBC: STREAM DX, INC.            Topic: 300

    PROJECT SUMMARY ABSTRACT Lower urinary tract symptoms LUTS is one of the most common medical problems among older men affecting of men by the time they reach years of age and by the time they reach the age of LUTS is a progressive disease that has been shown to significantly increase the risk of depression and reduce quality of life Due to this early detection and active man ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. ARF6 Inhibitors for Treatment of Acute Lung Injury

    SBC: NAVIGEN, INC.            Topic: NHLBI

    PROJECT SUMMARY Acute lung injury ALI and acute respiratory distress syndrome ARDS result from a common pathogenic process pulmonary injury or infection triggers an overwhelming inflammatory response cytokine storm that results in increased endothelial and epithelial permeability and efflux of inflammatory cells protein and water from the vascular system into the alveolar space The fu ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR Phase I: Novel Device for detecting changes in the esophageal lumen using single point ultrasonic transducers

    SBC: RefloDx LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will benefit nearly 6 million children per year who are suspected of having abnormal Gastroesophageal Reflux (GER) which can lead to a more serious condition with numerous complications referred to as Gastroesophageal Reflux Disease (GERD). Current detection paradigms include costly and invasi ...

    SBIR Phase I 2017 National Science Foundation
  10. SBIR Phase I: Multi-Sensory Therapy Program for Children with Autism Spectrum Disorder

    SBC: Teaching It Right, LLC            Topic: EA

    This project will develop a multi-sensory therapy program for children diagnosed with Autism Spectrum Disorder by improving eye contact. Children with Autism Spectrum Disorder do not make eye contact readily and eye contact is a key component in progressing social behavior. Current methodologies to assist these children in maximizing their capabilities are out of reach for many, costing families t ...

    SBIR Phase I 2017 National Science Foundation

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