Award Data

DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

Nanoscale infrared detectors are emerging as a potentially powerful alternative to traditional infrared detector technologies. The University of New Mexico has developed dots in a double well (DDWELL) quantum dot infrared photodetectors which have a spectral responsivity that can be tuned by controlling the bias voltage applied. In this Phase II effort, Polaris Sensor and UNM would fabricate a g ...

The Oceanit¡¦s/APL Foveal InfraRed Search and Track (FIRST) prototype is a dual channel cryogenic WFOV optical sensor system. FIRST provides multifaceted support for an airborne IR search and track and uses the unique Multi-target-tracking Optical Sensor-array Technology (MOST) sensor chip, which has been developed at MDA. FIRST supports instantaneous field-of-view up to 90 degrees, with 360 deg ...

Our objective is to develop advanced mediator architectures for efficient electron transfer in enzymatic fuel cells (EFCs) for low power systems. The proposed EFC will leverage ongoing research at both CFDRC and Michigan State University to provide a fully-integrated lightweight, low-cost, manufacturable, and renewable power supply, for various military and civilian applications. EFC systems offer ...

DESCRIPTION (provided by applicant): Patient Provider Communications will develop EloquenceTM based on data acquired from research conducted by the University of Michigan School of Nursing addressing the specific aims and hypothesis. This project extends the research team's preliminary findings on the development of technology to improve communication with critically ill patients using patient des ...

DESCRIPTION (provided by applicant): The goal of this STTR project is to develop innovative human tumor microenvironment (TM) assays for use as screening tools in the identification of new anti-tumor therapeutics. Novel assay technologies are needed for the discovery of new drugs, and combinations of drugs currently in clinical use, that are effective in the prevention and treatment of cancer. Thi ...

DESCRIPTION (provided by applicant): Molecular interactions are central to the understanding of basic biology and cellular function, are paramount to all molecular assays (research and in vitro diagnostics), are essential in biomarker discovery and critical toward evaluating therapeutics. However, the tools available to quantify these interactions have limitations, in so far as they either rely up ...

Accurate real-time waterborne pathogen detection is of paramount importance to security of U.S. military forces and installations. Fieldable high-throughput pathogen concentration is a critical analytical need for enhanced detection performance. Existing concentration methods are time-consuming, bulky, labor-intensive, power- and reagent-hungry, and consequently ill-suited for battlefield deployme ...

The overall objective of this STTR project is to develop a comprehensive CAD environment for design and optimization of antennas and arrays on complex platforms such as topsides of naval surface combatants. EMAG Technologies Inc. has teamed up with the University of Michigan to develop a novel solution for placement of antennas on such platforms using a number of new physics-based genetic algorith ...

Hypersonic missile defense systems are being designed to reach global threats. During flight, external surfaces are predicted to reach temperatures in excess of 2200C. As a result, innovative, high performance thermal protection systems (TPS) are of great demand. Among ultra-high temperature ceramics (UHTC), it is well known that ZrB2- and HfB2-based materials have high melting temperatures and ...