Award Data

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

Automatic Speech Recognition (ASR) allows trainees to practice verbal communication skills in representative training environments without the need for human role players. However, these technologies have yet to become a feature of most training systems. Building on Phase I work, SoarTech along with our academic partners at UC Davis, proposes developing Soliloquy, a novel interface that allows non ...

Environment-security researchers and practitioners must overcome several technical challenges in the course of their efforts. In the absence of an open-community platform, each researcher or institution compiles and curates their own data repositories, analytical tools, and computational environments. This results in significant duplication of effort, limits the replication and validation of resea ...

Pulse voltammetry techniques, coupled with model-based analysis tools, provide a number of advantages for quantitative analysis of electrochemically active materials that govern the performance of batteries and fuel cells. In prior Phase I and II research, CFD Research developed and validated computational models in software that reads voltammogram data from laboratory instruments; predicts the re ...

The U.S. Navy currently utilizes a number of towed systems from surface ship and submarines for sensing and communication applications. In a number of these cases, a tow cable extends either down from a surface ship or up from a submarine through the upper part of the water column where seawater temperature can be both highly variable vs. depth and dynamic in time and geographic location. Having a ...

The technical objectives of this proposal are: 1) demonstrate a single-element, 4.6 micron-emitting quantum-cascade-laser (QCL) with > 40 % continuous-wave (CW) wallplug efficiency (WPE) at room temperature; (2) perform a comprehensive simulation to achieve a design for a monolithic QCL operating in a single spatial mode to 10 W CW output power; 3) perform a thermal-management analysis for the des ...

One important challenge for the reliable prediction of liquid fuel effects on the combustion in aviation combustors and augmentors is the accurate modeling of underlying physical processes, involving the evaporation of fuels, preferential vaporization, scalar mixing and ignition. LES methodologies are required to accurately capture these transient and inherently unsteady combustion processes. In t ...

With the advent of the Navy’s newest classes of all-electric vessels, the interdependence and functional correlation of the power plant with other mission-critical ship systems such as integrated cooling, weapons, navigation, air surveillance, and IT control network systems, maintaining optimal oversight and control of power distribution aboard ship becomes increasingly challenging. As the opera ...

Evidence-based guidelines derived from the learning sciences literature can be applied to training-requirements decisions. However, accessing the state-of-the-art in the learning sciences and applying its lessons to specific training design and analysis questions can be difficult, especially for those not already familiar with the learning sciences. ARCHIMEDES, the software tool proposed in this e ...

In order to enable reliable predictions based on full scale vehicle simulations relevant to high-speed ISR missions, detailed interactions among various nonequilibrium physical phenomena and their coupling to turbulent flow structures, characterized by a broad range of length/time scales, need to be accurately modeled. Through this Phase II STTR project new computational tools for reliable and eff ...