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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Client-Accessible Design Interface for Physical Models

    SBC: 3D Molecular Designs LLC            Topic: N/A

    DESCRIPTION (provided by applicant): An accurate physical model of a protein, based on its atomic coordinate data and created by rapid prototyping technology, is an effective new tool to communicate the essential details of a new structure to the bioc

    SBIR Phase I 2004 Department of Health and Human Services
  2. Tools for Targeted Delivery of DNA into Mammalian Cells

    SBC: ALPHA UNIVERSE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Viral vectors are the most efficient tools currently available for genetic modification of mammalian cells in vitro and in vivo. However, because protocols for the incorporation of DNA of interest into viral particles

    SBIR Phase I 2004 Department of Health and Human Services
  3. Release of Angiogenic Inhibitors for Macular Edema

    SBC: Charlesson, LLC            Topic: N/A

    DESCRIPTION (provided by applicant) Increased vascular permeability or vascular leakage in the retina is an early and common feature of diabetic retinopathy and can result in diabetic macular edema. Vascular leakage is also responsible for cystoid mac

    SBIR Phase I 2004 Department of Health and Human Services
  4. Rare Event Imaging

    SBC: Sciperio, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Rare-event imaging has profound implications for the early identification of potentially correctable terminal diseases, especially for cancer. What is required is a highly accurate "routine" test to be given to all

    SBIR Phase II 2004 Department of Health and Human Services
  5. Automated, portable, concurrent, WMD detection system

    SBC: Concurrent Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. A ...

    STTR Phase I 2004 Department of Health and Human Services
  6. Testing An Interactive website for Hormone Replacement

    SBC: EAKER EPIDEMIOLOGY ENTERPRISES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II Small Business Innovation Research (SBIR) grant application proposes to test a prototype model developed under a Phase I SBIR grant on postmenopausal hormone therapy (HT). Using the technology of the Inte

    SBIR Phase II 2004 Department of Health and Human Services
  7. Development of a Breath Analyzer for Asthma Screening

    SBC: Ekips Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): An innovative instrument for measuring exhaled compounds was demonstrated in Phase I of this project. The novel breath monitor (Breathmeter TM) consists of a tunable mid-IR diode laser, a long optical resonator, and el

    SBIR Phase II 2004 Department of Health and Human Services
  8. Discovery of Anti-Bioweapon Agents in BAC Libraries

    SBC: EMETAGEN, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotics are an essential component in bio-defense preparedness. Soil microorganisms were a major source of antibiotics during the 20th century, yet antibiotic discovery is now severely limited. A primary reason is that drug discovery from microorganisms has been confined to those microbes that can be recovered by laboratory cultivation, yielding high rates ...

    STTR Phase I 2004 Department of Health and Human Services
  9. Detecting Early Emerging Drug-Resistant HIV Populations

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of human immunodeficiency virus type 1 (HIV) infection with antiretroviral agents invariably leads to selection and accumulation of drug-resistant mutants that arise due to the intrinsically low fidelity of HIV polymerase. Early detection of these growing variants may be clinically relevant. Before the level of clinical importance can be ascertained, ...

    STTR Phase I 2004 Department of Health and Human Services
  10. Rapid Detection of Agents that Cause Respiratory Disease

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of this proposed project is to develop a clinical diagnostic in three years that targets 15 agents that cause infections in the respiratory tract that may be misdiagnosed for the SARS virus. Our prel

    SBIR Phase I 2004 Department of Health and Human Services

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