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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Adaptive Artificial Intelligence for Next-Generation Conflict Simulation

    SBC: John Tiller Software, Inc            Topic: AF03T022

    This proposal is for the design and development of a challenging, adaptable, and extendible AI system for use in state-of-the-art computer-based wargames. The development will result in a 3rd generation computer wargame based on modern air power conflict and the ability to apply the technology developed for this project in other wargames ranging from tactical ground-based warfare to naval conflic ...

    STTR Phase II 2004 Department of DefenseAir Force
  2. All-Nitrogen or High-Nitrogen Compounds as High Energy Density Materials

    SBC: ERC, INC.            Topic: AF04T003

    During Phase I of the proposed program, ERC-Incorporated proposes to identify novel promising polynitrogen candidates by means of theoretical calculations. Furthermore, preliminary tests will be carried out to explore the feasibility of synthesizing the most promising candidates. High-nitrogen compounds constitute a second area of significant interest. It is well known that the insertion of one he ...

    STTR Phase I 2004 Department of DefenseAir Force
  3. Automated, portable, concurrent, WMD detection system

    SBC: Concurrent Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. A ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Biofilm Restoration for Contaminated Army Sites

    SBC: Mse Technology Applications, Inc.            Topic: N/A

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase I 2004 Department of DefenseArmy
  5. Biofilm Restoration for Contaminated Army Sites

    SBC: Mse Technology Applications, Inc.            Topic: ARMY03T13

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase II 2004 Department of DefenseArmy
  6. Cardiac Interactions of New Adriamycin Analogs and Taxol

    SBC: GEM Pharmaceuticals            Topic: N/A

    DESCRIPTION (provided by applicant): Paclitaxel (Taxol) and doxorubicin (DOX, Adriamycin) are chemotherapeutic drugs used in treatment of metastatic breast cancer. When used individually, they produce a 30-40 percent response rate. When combined, using high doses of DOX (450-550 mg/m2), the response rate is increased to 85-95 percent. This represents a significant improvement in tumor responsivene ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Design and Testing of a Water Based Fire Extinguishing System for On-Board Hydrogen Peroxide Fires

    SBC: STREAMLINE AUTOMATION LLC            Topic: MDA04T004

    The Air Force has demonstrated that a water is capable of extinguishing comparable H2O2 oxidizer fires with 23 pounds of water vs 67 pounds of halon. Recent advances in sensor technology make it possible to detect an H2O2 leak prior to ignition, or to rapidly detect ignition in order to initiate fire protection system water flow. Recent findings by Streamline Automation also indicate that fire e ...

    STTR Phase I 2004 Department of DefenseMissile Defense Agency
  8. Detecting Early Emerging Drug-Resistant HIV Populations

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of human immunodeficiency virus type 1 (HIV) infection with antiretroviral agents invariably leads to selection and accumulation of drug-resistant mutants that arise due to the intrinsically low fidelity of HIV polymerase. Early detection of these growing variants may be clinically relevant. Before the level of clinical importance can be ascertained, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Genome-wide Drosophia RNAi Resource

    SBC: OPEN BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Genetics has provided one of the most discerning and powerful approaches to the dissection of biological function and Drosophila has served as a major model organism for such analyses, many of which have been probed processes relevant to human health. Now gene inactivation by RNAi is revolutionizing genetic approaches. By making possible extremely rapid whole g ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Discovery of Anti-Bioweapon Agents in BAC Libraries

    SBC: EMETAGEN, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotics are an essential component in bio-defense preparedness. Soil microorganisms were a major source of antibiotics during the 20th century, yet antibiotic discovery is now severely limited. A primary reason is that drug discovery from microorganisms has been confined to those microbes that can be recovered by laboratory cultivation, yielding high rates ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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