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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. STTR Friction Stir Processing for Superplastic Forming

    SBC: FRICTION STIR LINK, INC.            Topic: N06T038

    Friction Stir Processing (FSP) is an emerging technology that can be used to pre or post-process a range of materials, including aluminum, to locally modify material properties. It is known that FSP can be used to enhance material properties for improved superplastic forming (SPF) behavior of aluminum. This can potentially allow for dramatic cost reductions of SPF and aluminum fabrications, all ...

    STTR Phase I 2006 Department of DefenseNavy
  2. Development of Plant Derived Antibodies for Drugs Abuse

    SBC: INTERVEXION THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this combination Phase I / Phase II STTR project is to test the hypothesis that anti-drug monoclonal antibodies are a safe and effective therapy for the medical problems associated with phencyclidine (PCP) abuse. There are currently no specific medications for treating the medical problems caused by acute or chronic PCP abuse. Thus, long-lasting m ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Merit of MRI Perfusion Targets for Radiotherapy Planning

    SBC: PRISM CLINICAL IMAGING INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I STTR proposal is to seamlessly integrate MRI (magnetic resonance imaging)- derived perfusion measurements into the radiation treatment (RT) planning systems for brain tumor patients. Currently the MRI and CT (computed tomography) information that is used to define the RT target volumes is based on information about brain anatomy, and no ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Neuroimaging Aids for Treatment of CNS Vision Pathology

    SBC: PRISM CLINICAL IMAGING INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop functional magnetic resonance imaging (fMRI) tools for assessing and treating human patients with a brain neoplasm or other focal pathology involving the visual system, especially visual cortex. Such patients can face difficult decisions balancing aggressive, invasive treatment of the pathology with side- effects involvin ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Intravenous non-viral gene therapy for phenylketonuria (PKU)

    SBC: MIRUS BIO CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop a safe, effective, non-viral, muscle-directed gene therapy approach to the treatment of phenylketonuria (PKU), a relatively common inborn error of metabolism. Contemporary dietary therapy for PKU, although preventing the major manifestations of the disease (seizures, microcephaly, mental retardation), requires life ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Intravenous non-viral gene therapy for amyotrophic lateral sclerosis

    SBC: MIRUS BIO CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is the most prevalent lethal motor neuron disease in adults and there is no effective therapy available. The primary defect in ALS is the degeneration of upper and lower motor neurons causing subsequent muscle weakness and atrophy. Neurotrophic factors have potential in therapy for ALS because they show a protective effect on ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Neuroprotective Drugs for Alzheimer's Disease

    SBC: MITHRIDION, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is an enormous unmet need for disease-modifying drugs that affect the pathogenesis of Alzheimer's disease (AD). Currently available drugs provide only modest cognitive improvement and may delay the onset of disability, but do not halt the disease process. AD is the most common form of dementia, deeply affecting the lives of an estimated 4.5 million Americ ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Infrared (IR) Sensor Components for Missile Defense

    SBC: NANO LIGHT            Topic: MDA06T011

    The objective of this proposal is to further explore PbSnSe detector array on Si substrate. Two approaches are proposed. One is a zero-risk incremental advance that employs a new growth condition to reduce the dislocation density. Another approach is a novel fabrication technique with high-risk but it could enable revolutionary rather than evolutionary advances. IV-VI semiconductors such as Pb1-x ...

    STTR Phase I 2006 Department of DefenseMissile Defense Agency
  9. Development of Lightweight and Low Cost Advanced Structural Materials for Off-board Surface Vessels (OBVs)

    SBC: PacMar Technologies LLC            Topic: N06T021

    The Navatek, Ltd. Team will successfully demonstrate the feasibility of using Fiber Reinforced Composites (FRC) materials to significantly reduce the weight of the (hull) structure of the Littoral Combat Ship (LCS) Unmanned Surface Vehicle (USV). We will use as a baseline for comparison our entrapment tunnel monohull (ETM) hullform. This hullform was selected by the Navy to satisfy the LCS (Flight ...

    STTR Phase I 2006 Department of DefenseNavy
  10. Gaseous, Liquid, and Gelled Propellant Hypergolic Reaction Mechanisms

    SBC: Orbital Technologies Corporation            Topic: A06T001

    ORBITEC proposes a parallel computational and experimental effort to understand the phenomena underlying hypergolic ignition of gelled propellants. Gelled hypergolic propellants offer many benefits to modern propulsion systems. They offer good insensitive munitions characteristics and versatile performance. However, gelled propellants typically exhibit longer ignition delays than liquid propell ...

    STTR Phase I 2006 Department of DefenseArmy
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