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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Automated, portable, concurrent, WMD detection system

    SBC: Concurrent Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. A ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Discovery of Anti-Bioweapon Agents in BAC Libraries

    SBC: EMETAGEN, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotics are an essential component in bio-defense preparedness. Soil microorganisms were a major source of antibiotics during the 20th century, yet antibiotic discovery is now severely limited. A primary reason is that drug discovery from microorganisms has been confined to those microbes that can be recovered by laboratory cultivation, yielding high rates ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Detecting Early Emerging Drug-Resistant HIV Populations

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of human immunodeficiency virus type 1 (HIV) infection with antiretroviral agents invariably leads to selection and accumulation of drug-resistant mutants that arise due to the intrinsically low fidelity of HIV polymerase. Early detection of these growing variants may be clinically relevant. Before the level of clinical importance can be ascertained, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Pharmacophylogenomic Dates for the Master Catalog

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will enhance the MASTERCATALOG, EraGen's product that combines an evolutionarily organized protein sequence database with tools to enable phylogenomics analysis. This will help maintain the commercial advantage of the MASTERCATALOG over public databases and tools, and help ensure that the MASTERCATALOG continues to enjoy its status as the "best in ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Multidisciplinary Optimization of Naval Ship Design and Mission Effectiveness

    SBC: GLOBAL TECHNOLOGY CONNECTION, INC.            Topic: N03T026

    The objective of this program is to apply newly developed Multidisciplinary Optimization (MDO) methods to the ship design optimization process. This proposal presents the background and work necessary to adapt methodologies for the design of complex systems developed at the Aerospace Systems Design Laboratory (ASDL) at Georgia Tech under the sponsorship of the Office of Naval Research, in support ...

    STTR Phase II 2004 Department of DefenseNavy
  6. On-Line Trajectory Optimization for Autonomous Air Vehicles

    SBC: GUIDED SYSTEMS TECHNOLOGIES, INC.            Topic: AF02T002

    Successful operation of next-generation unmanned air vehicles will demand a high level of autonomy. Autonomous low-level operation in a high-threat environment dictates a need for on-board, robust, reliable and efficient trajectory optimization. The proposed effort will develop and demonstrate an innovative combination of traditional analytical and numerical solution procedures to produce effici ...

    STTR Phase II 2004 Department of DefenseAir Force
  7. Sonobuoy Tube Launched UAV

    SBC: GUIDED SYSTEMS TECHNOLOGIES, INC.            Topic: N04T004

    Expendable, sonobuoy tube-launched unmanned aerial vehicles employing a variety of sensor systems are recognized as providing an economical means to enhance P-3 aircraft operations and assure crew safety. The proposed phase I program develops a preliminary design for a tube-launched vehicle by optimizing the system design parameters along optimized trajectories that are developed for a representa ...

    STTR Phase I 2004 Department of DefenseNavy
  8. Development of a Next-Generation Shock Wave Lithotripter

    SBC: HEALTHTRONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Since the introduction of shock wave lithotripsy (SWL) in the earlier 1980s by Domier Medical System, the technology of SWL has evolved significantly in terms of the means for shock wave generation, focusing, patient coupling, and stone location. However, the fundamental working principle of SWL remains unchanged despite of these technical developments. During ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. POSITRON EMISSION TOMOGRAPHY GUIDED PROSTATE BIOPSY

    SBC: I.SOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Prostate cancer imaging with positron emission tomography (PET) has been facilitated by the recent development of the radioactive tracer fluorine-18 fluorocholine (F-18 FCH). Like other substrates for the enzyme choline kinase, F-18 FCH demonstrates increased accumulation in malignant cells. In addition to whole-body cancer staging, F-18 FCH PET may potentia ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid and Robust Dynamics-based Nondestructive Method to Monitor Structural Health

    SBC: Millennium Dynamics Corporation            Topic: AF04T016

    The objective of this proposal is to demonstrate the feasibility of detecting damage in structures using Laser Doppler Vibrometry (LDV) and further lead to the development of a robust aerospace structural health monitoring system. The proposed concept is based on use of LDV to measure velocities and displacements associated with high frequency operational deflection shapes as well as lamb waves. ...

    STTR Phase I 2004 Department of DefenseAir Force
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