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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Small Animal Handling Devices for Multiplatform Imaging

    SBC: ASI INSTRUMENTS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Small animal imaging initiatives are growing rapidly due to the enormous potential for improved understanding and treatment of human disease through animal imaging. At present, every radiologic modality available for use in humans has been adapted for small animal use. Other modalities have been devised solely for the purpose of in vivo imaging of research anim ...

    STTR Phase I 2004 Department of Health and Human Services
  2. Purification and crystallization of human 12-LOX enzymes

    SBC: Biomide Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Metabolism of arachidonic acid by 12-lipoxygenase results in the formation of 12(S)-hydroxy eicosatetraenoic acid, which exhibits profound biological activity and plays an important role in tumor cell proliferation, motility, invasiveness, angiogenesis, and inhibition of apoptosis, all properties essential for the growth and metastasis of cancer cells. Arachido ...

    STTR Phase I 2004 Department of Health and Human Services
  3. Fast Laser Pulse Shaping for Molecular Control and CB Detection

    SBC: Biophotonic Solutions, Inc.            Topic: A04T008

    Monitoring the air for potential chemical and biological agents (from terrorist threats or from industrial contamination) has become a necessity. Our proposal objective is to develop device capable of fast (1 second), accurate (even in a chemically complex environment), robust (stand alone, closed-loop, and portable), and reproducible sensing. Operationally, the device interfaces with a commercial ...

    STTR Phase I 2004 Department of DefenseArmy
  4. Biofilm Restoration for Contaminated Army Sites

    SBC: CENTER FOR INNNOVATION, INC.            Topic: N/A

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase I 2004 Department of DefenseArmy
  5. Biofilm Restoration for Contaminated Army Sites

    SBC: CENTER FOR INNNOVATION, INC.            Topic: ARMY03T13

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase II 2004 Department of DefenseArmy
  6. Automated, portable, concurrent, WMD detection system

    SBC: Concurrent Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. A ...

    STTR Phase I 2004 Department of Health and Human Services
  7. Highly Robust, Temperature-Stable, Nano-structured Fluoropolymers for Battlefield Resuscitation Applications

    SBC: DENDRITECH, INC            Topic: A04T024

    The aim of this research program is to evaluate highly fluorinated yet water soluble, nano-scaled polymers for use in battlefield resuscitation applications where highly efficient oxygen transport is required. These polymers will represent a quantum leap over current artificial oxygen transport technology, which includes modified hemoglobin (e.g., crosslinked human, animal and recombinant hemoglob ...

    STTR Phase I 2004 Department of DefenseArmy
  8. "A molecular signature of cell invasion in breast ca.

    SBC: DETROIT R & D, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research project is to unveil the molecular signature of tumor cell invasion. Tumor invasion and metastasis are complex processes involving extracellular matrix (ECM) degrading proteinase activity and cell migration through the ECMs. Since mounting evidence suggests that ras expression serves as a marker for tumor aggressiveness ...

    STTR Phase I 2004 Department of Health and Human Services
  9. The Use of Boron Nitride for Improved Cold-Cathode Electron Field Emission Technology

    SBC: Electrodynamic Applications Inc            Topic: AF03T016

    Low-power Hall thrusters offer potentially important advantages for certain military applications but issues of lifetime and efficiency degradation at lower powers are issues hindering its utilization. A factor impacting efficiency is that the state-of-the-art techniques for electron generation used for neutralization (such as hollow cathodes operating on the same propellant as the thruster) do n ...

    STTR Phase II 2004 Department of DefenseAir Force
  10. Discovery of Anti-Bioweapon Agents in BAC Libraries

    SBC: EMETAGEN, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotics are an essential component in bio-defense preparedness. Soil microorganisms were a major source of antibiotics during the 20th century, yet antibiotic discovery is now severely limited. A primary reason is that drug discovery from microorganisms has been confined to those microbes that can be recovered by laboratory cultivation, yielding high rates ...

    STTR Phase I 2004 Department of Health and Human Services
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