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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biofilm Restoration for Contaminated Army Sites

    SBC: Mse Technology Applications, Inc.            Topic: N/A

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase I 2004 Department of DefenseArmy
  2. Biofilm Restoration for Contaminated Army Sites

    SBC: Mse Technology Applications, Inc.            Topic: ARMY03T13

    Many Unites States Army, and other Department of Defense (DoD) sites, are contaminated with a variety of contaminants including highly energetic compounds, such as 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), chlorinated aliphatics (such as trichloroethylene,TCE) and chlorinated aromatics. These compounds often persist in soil or groundwater for extended periods of t ...

    STTR Phase II 2004 Department of DefenseArmy
  3. Automated, portable, concurrent, WMD detection system

    SBC: Concurrent Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. A ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Discovery of Anti-Bioweapon Agents in BAC Libraries

    SBC: EMETAGEN, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Antibiotics are an essential component in bio-defense preparedness. Soil microorganisms were a major source of antibiotics during the 20th century, yet antibiotic discovery is now severely limited. A primary reason is that drug discovery from microorganisms has been confined to those microbes that can be recovered by laboratory cultivation, yielding high rates ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Detecting Early Emerging Drug-Resistant HIV Populations

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of human immunodeficiency virus type 1 (HIV) infection with antiretroviral agents invariably leads to selection and accumulation of drug-resistant mutants that arise due to the intrinsically low fidelity of HIV polymerase. Early detection of these growing variants may be clinically relevant. Before the level of clinical importance can be ascertained, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Pharmacophylogenomic Dates for the Master Catalog

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will enhance the MASTERCATALOG, EraGen's product that combines an evolutionarily organized protein sequence database with tools to enable phylogenomics analysis. This will help maintain the commercial advantage of the MASTERCATALOG over public databases and tools, and help ensure that the MASTERCATALOG continues to enjoy its status as the "best in ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Novel SiGe Devices for Cryogenic Power Electronics

    SBC: GPD Optoelectronics Corporation            Topic: ST041002

    It is predicted that systems for power generation, power distribution and electric propulsion on ships and aerospace vehicles could be made smaller, lighter, more efficient, more versatile, and lower maintenance by operating these systems-partly or entirely-at cryogenic temperatures. We propose to demonstrate the advantages of cryogenic operation in regard to electronic components, specifically se ...

    STTR Phase I 2004 Department of DefenseDefense Advanced Research Projects Agency
  8. POSITRON EMISSION TOMOGRAPHY GUIDED PROSTATE BIOPSY

    SBC: I.SOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Prostate cancer imaging with positron emission tomography (PET) has been facilitated by the recent development of the radioactive tracer fluorine-18 fluorocholine (F-18 FCH). Like other substrates for the enzyme choline kinase, F-18 FCH demonstrates increased accumulation in malignant cells. In addition to whole-body cancer staging, F-18 FCH PET may potentia ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Ruminant B-Lymphocyte Yellow Fluorescent Protein Aggregation Bioassay for Elk Chronic Wasting Disease

    SBC: Nomadics, Inc.            Topic: A04T027

    The goal of the proposed research is to develop a cell culture model for elk chronic wasting disease (CWD) prion propagation that can be used as a bioassay for detecting CWD. Our goal will be accomplished by bioengineering a bovine B-lymphocyte cell (B-cell) line to surface express elk PrPc fused to yellow fluorescent protein (YFP). Interaction of these B-cells with infectious, mis-folded, proteas ...

    STTR Phase I 2004 Department of DefenseArmy
  10. Natural feedstocks for diversity oriented synthesis

    SBC: Promiliad Biopharma Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR application requests funds to support the transfer of specific synthetic expertise and methodologies from the Wright Group at Dartmouth College to investigators at Promiliad Biopharma in an effort to reduce Promiliad's REBACS strategy to the level of practice. These efforts will focus on the use of a high-complexity feedstock, nonactic acid, as the p ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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