Award Data

This program will further the development of large area freestanding GaN substrates (>100mm) and develop a bulk GaN substrate characterization protocol to help reduce the variability in GaN homoepitaxial growth results which have prevented low cost, high voltage, vertical GaN power devices from being realized in an economically viable way.

The U.S. Navy currently utilizes a number of towed systems from surface ship and submarines for sensing and communication applications. In a number of these cases, a tow cable extends either down from a surface ship or up from a submarine through the upper part of the water column where seawater temperature can be both highly variable vs. depth and dynamic in time and geographic location. Having a ...

For this Phase 1 Small Business Technology Transfer (STTR) project, Blackmore Sensors and Analytics and university partner Montana State University will investigate the use of coherent frequency modulated continuous wave (FMCW) ladar/lidar and digital holography techniques for improved performance of active imaging through fog. Coherent range, Doppler, and polarization selective digital holography ...

Additive manufacturing (AM) fills a technical need for the US Navy to produce on-site, on-demand, cost efficient parts. However, the lack of established procedures for AM machines and processes introduces significant variability in their mechanical behavior. A high throughput method is needed to characterize the variability in the mechanical properties of AM materials using large statistics. To me ...

Oceanit proposes to develop and demonstrate novel, tailored, designer separator materials with optimized properties to maximize lithium-ion cell/battery performance, life, safety and reliability.

The global contraceptives market was valued at $billion inand is expected to grow at a CAGR offromtoto reach an estimated value of $billion inThe contraceptive market consists of short term methods such as condoms and oral contraceptionlong term methods including implants and IUDsand permanent methods such as tubal ligations and vasectomiesEppin Pharmaandapos s product has a unique set of characte ...

Project SummaryOver $billion is spent annually in the US treating chronicnon healing woundsmany of which face lifethreatening complications due to infectionsWound infections are difficult to treat due to the frequency of antibiotic resistance as well as the formation of biofilmsa community of bacteria covered by an extracellular polymeric substanceBiofilm related infections can result in a substan ...

Abstract This project seeks to develop the next generation pro CARs that are inactive in normal tissues but selectively activated in the tumor microenvironmentTMEThe project is based on our previous development of a novel class of chimeric antigen receptors on the basis of single domain antibody mimics that recognize ErbB family membersSDAErbBon the surface of cancer cellsWe propose two specific a ...

PROJECT SUMMARY NETosis was identified as a distinct mode of cell death in neutrophils more than a decade agoDysregulation of NETosis has been implicated in the etiology of human pathologies such as preeclampsiasickle cell diseasesystemic lupus erythematosusmultiple sclerosisrheumatoid arthritissepsiscystic fibrosislupus nephritisand coagulopathies that include cancer associated thrombosisThe lite ...

PROJECT SUMMARY ABSTRACT The objective of this proposal is to develop an efficient and robust method to epigenetically reprogram na ve human T cells into regulatory T cellsTregsthat can prevent graft versus host diseaseGvHDOur short term goal for Phase I of the STTR award is to demonstrate that we can epigenetically reprogram na ve T cells using CRISPR Casbased technology into immunosuppressive ce ...