Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Topical selective T-type blockers for the treatment of neuropathic pain

    SBC: Dermaxon LLC            Topic: 105

    Project SummaryAbstract Paclitaxel is widely used throughout the field of oncology with indications for the treatment of a number of solid tumorsThe most commonly reported neurotoxic effect of paclitaxel is peripheral sensory neuropathy which often limits the dose and frequency of paclitaxel treatmentNeuropathic pain management is currently aimed only at reducing symptoms and treatment of chronic ...

    STTR Phase I 2018 Department of Health and Human Services
  2. Selection and Development of a Lead Biologic for Treating Mitochondrial Disorders

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos sRecent discoveries support that mitochondrial dysfunction can be overcome to treat age related declineCyteGenandapos s hypothesis is that exercise induces the secretion of bloodborne proteins that act system ...

    STTR Phase I 2018 Department of Health and Human Services
  3. PET Imaging Agent for Myocardial Infarction

    SBC: HEXAKIT, INC.            Topic: NHLBI

    Project Summary Each year millions of individuals suffer from myocardial infarctionMIor heart attackDiagnosis of MI is dependent on a complex set of tests which include imagingcardiac troponin levels in plasmaand electrocardiogramViability assessment and myocardial perfusion imaging by radiolabeled tracers has the most impact on the diagnosis and risk assessment of MIHoweverperfusion scans are una ...

    STTR Phase I 2018 Department of Health and Human Services
  4. Improving STEM learning through digital technology simulating authentic research

    SBC: MEADOWLARK SCIENCE AND EDUCATION, LLC            Topic: 500

    Novel and effective techniques for imparting STEM based knowledge and concepts are increasingly in demand as our world becomes progressively computerized and complexWhile traditional teaching approaches have worked well in the past for many areas of studyresearch has shown that traditional teaching methods may diminish student engagement in scientific studieswhich are especially dynamic and consta ...

    STTR Phase I 2018 Department of Health and Human Services
  5. CCN3-derrived peptides to treat liver injury

    SBC: BLR Bio            Topic: 200

    Project Summary Chronic liver disease is becoming a major public health issue with estimates of up toprevalence of nonalcoholic fatty liver diseaseNAFLDandwith non alcoholic steatohepatitisNASHin the U SLiver disease and cirrhosis was theth leading cause of mortality in the U SinObesity and metabolic syndrome are important causes of fatty liver disease or steatosiswith NAFLD rates of up toin typed ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Single application thixotropic antibiotic delivery systems for otitis externa

    SBC: Promiliad Biopharma Incorporated            Topic: NIDCD

    The proposal seeks to initiate the development of a tetraethyl orthosilicate based thixotropic antibiotic delivery systems for the treatment of otitis externa and prevention of malignant otitis externaThis study will set the foundation for the development of point of caresingle application thixotropic drug delivery platform technologies for otic therapeutics PROJECT SUMMARY Outer ear infectionsoti ...

    STTR Phase I 2018 Department of Health and Human Services
  7. Wearable Shear Wave Tensiometry for Tracking Tendon Load during Dynamic Movement

    SBC: Design Concepts, Incorporated            Topic: NIAMS

    Project Summary The long term goal of this project is to develop a wirelesswearable system to estimate the tension in tendons of the legs during dynamic movementsTendon tension provides an estimate of muscle forcewhich is important information for understanding biomechanical behavior in all types of movementthough it has previously been difficult to measureRecent advances have shown that skin moun ...

    STTR Phase I 2018 Department of Health and Human Services
  8. Quantitative Magnetic Resonance Imaging Phantoms

    SBC: Calimetrix, LLC            Topic: NIBIB

    PROJECT SUMMARYThe overall goal of this Phase I proposal is to designdevelop and test the feasibility of advanced quantitative magnetic resonance imagingMRIphantoms that mimic the simultaneous presence of fatiron and fibrosisFatiron and fibrosis are three principal histological coexisting features of many important disease statesPhantoms are highly controlled test objects that accurately reflect t ...

    STTR Phase I 2018 Department of Health and Human Services
  9. Gene Therapy for Type 1 Diabetes

    SBC: Endsulin LLC            Topic: NIDDK

    TypeDiabetes MellitusT DMis an increasingly prevalent form of diabetes in which the insulin producingcells of the pancreas are destroyed by an autoimmune attackand as a resultno endogenous insulin is producedMost often diagnosed in childrenmillion Americans suffer from T DMandnew cases are diagnosed annually worldwideT DM profoundly impacts patientshealth and quality of life due to the constant ne ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Active Imaging through Fog

    SBC: Blackmore Sensors and Analytics, Inc.            Topic: N18AT021

    For this Phase 1 Small Business Technology Transfer (STTR) project, Blackmore Sensors and Analytics and university partner Montana State University will investigate the use of coherent frequency modulated continuous wave (FMCW) ladar/lidar and digital holography techniques for improved performance of active imaging through fog. Coherent range, Doppler, and polarization selective digital holography ...

    STTR Phase I 2018 Department of DefenseNavy
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