Award Data

Adverse physiological events (PEs) have plagued warfighters piloting military aircraft, in particular PEs involving hypoxia and cockpit cabin decompression. Though there has been a large variety of research performed in trying to understand the problems and why theyre caused, there are inefficiencies due to the lack of standardized cross-laboratory protocols, procedures, and metrics. To address th ...

Airway compromise is the third leading cause of potentially preventable death on the battlefield. Current evaluation techniques of the airways associated with smoke inhalation injury are highly subjective and lack the sensitivity required of an accurate diagnostic and assessment tool. The problem of detection is further compounded by the late onset of symptoms that in many cases do not present unt ...

It is generally recognized that the human body transmits electro-magnetic fields (EMF). The Phase I program demonstrated a practical solution to detect these emissions. The technology was shown to be compatible for integration into wearable textiles. The Phase 2 program will focus on demonstrating the capability of discriminating between healthy and injury related EMF emissions such that it can be ...

There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

Approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, an even higher percentage (80%) of severe medical errors are related to miscommunication during handoffs (i.e., the transferring of information, responsibility, and authority for patient care from one provider to another). The TiER1 team proposes to address challe ...

Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...

Triton Systems will develop a novel approach to field-based disease and biochemical diagnostics through innovative use of extremely low cost bioanalytical devices.The proposed platform will provide a low cost, portable, and reliable diagnostic test for on-site use in austere and resource-limited environments.The devices will be highly durable, rugged, and easy to use without user-induced variation ...

In this topic, we plan to design a vital EMF sensor to work under any conditions. The sensor will be integrated with smart clothing and using e-textile materials.

Accurate assessment of burn depth and surface area are important to clinical decision-making regarding treatment. Initial assessment determines fluid requirements and transportation decisions to distant-care facilities. The clinician must determine if the wound will heal itself or whether excision and grafting are necessary for optimal wound healing. The standard of care remains visual inspection ...

Rodents serve as models for the human brain and behavior, and their calls give researchers a window into their mood. Unfortunately, rodent calls are ultrasonic, so a researcher must record a test and then play the audio back at a slower speed to manually categorize and count calls. Software does exist to accomplish this task, but it does not have the ease of use or accuracy that researchers want. ...