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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: Luna Innovations Incorporated            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  2. Brain Targeting Nanoparticle for Drug Delivery in Traumatic Brain Injury

    SBC: Weinberg Medical Physics, Inc.            Topic: DHA18A001

    There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  3. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  4. Situational Awareness for Mission Critical Ship Systems using Probabilistic Knowledge Graph

    SBC: INTELLIGENT FUSION TECHNOLOGY, INC.            Topic: N18AT009

    This effort proposes to develop situational awareness methodologies for mission critical ship system based on the state-of-the-art probabilistic knowledge graph (KG) and deep learning. The proposed KG approach can incorporate various data fusion technologies for analysis of unstructured data (text, images, etc.) and structured data (signal feeds, database items, etc.) for automated decision suppor ...

    STTR Phase I 2018 Department of DefenseNavy
  5. Nondestructive Evaluator for Polymer Ablatives (NEPAL)

    SBC: INTELLIGENT AUTOMATION, INC.            Topic: N18AT011

    Materials for thermal protection are required to protect structural components of space vehicles during the re-entry stage, missile launching systems, and solid rocket motors (SRMs). Polymer resins that have high char retention (e.g., phenolic resins) are the most common matrices in the composite materials for rigid thermal protection systems (TPSs) due to their tunable density, lower cost, and hi ...

    STTR Phase I 2018 Department of DefenseNavy
  6. Rapid Identification of Effects of Defects within Metal Additive Manufacturing (RIED-AM)

    SBC: INTELLIGENT AUTOMATION, INC.            Topic: N18AT013

    Additive manufacturing (AM) systems, especially metal AM, bring revolutionary capabilities, but suffer from a lack of understanding of the defects that exist within the components. In this research, based on selective experimental study and numerical simulations, we will develop an empirical database of defects and their effects on mechanical properties using Laser Powder Bed Fusion (LPBF) technol ...

    STTR Phase I 2018 Department of DefenseNavy
  7. Analysis of Dislocation Density, Recrystallization, and Residual Stress in 5XXX Aluminum using Laser Peening to mitigate Exfoliation Corrosion

    SBC: HEPBURN AND SONS LLC            Topic: N18AT016

    Hepburn and Sons LLC teaming with The Ohio State University, Center for Electron Microscopy and Analysis (CEMAS) propose to research and develop an innovative application of laser peening technology to mitigate exfoliation corrosion, a special type of inter-granular corrosion that occurs on the elongated grain boundaries. Strongly related, these Mg based alloys, when exposed to tensile stresses, c ...

    STTR Phase I 2018 Department of DefenseNavy
  8. Hot Filament CVD technology for disruptive, high-throughput SiC epitaxial growth reactors

    SBC: TrueNano, Inc            Topic: N18AT004

    TrueNano, Inc. will in collaboration with the University of Colorado and industry partners, develop a novel single-wafer, high-throughput hot filament CDV reactor for the growth of high quality silicon carbide (SiC) epitaxial layers, suitable for the next generation of power electronic devices and systems. This includes the design and simulation of the reactor, the development of a throughput mode ...

    STTR Phase I 2018 Department of DefenseNavy
  9. Cubic Boron Nitride Claddings for Friction Stir Tooling

    SBC: Plasma Processes, LLC            Topic: N18AT026

    Friction stir welding (FSW) is an attractive joining method where high strength low porosity welds can be attained. However, the high temperatures and forces required for welding high strength materials like steel require the use of exotic tools. Cubic boron nitride (cBN)-based tools offer attractive tool wear characteristics in steels, but are very costly. Conversely, refractory metal alloys are ...

    STTR Phase I 2018 Department of DefenseNavy
  10. Multi-Modal Sensing of Sensitization and Stress Corrosion Cracking Susceptibility in AA5xxx Alloys

    SBC: Luna Innovations Incorporated            Topic: N18AT010

    In order to travel faster, travel longer, and carry larger payloads, new Navy ships are being designed with light weight alloys and composite materials. High magnesium AA5xxx series alloys provide a high strength to weight ratio and excellent corrosion resistance, but suffer from sensitization as anodic ß precipitates (Al¬3Mg2) are form along grain boundaries due to a combination of elevated tem ...

    STTR Phase I 2018 Department of DefenseNavy
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