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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Modeling of Polytonic Dose Response Relationships

    SBC: LipoSeuticals Inc            Topic: DHP16C001

    Dose response relationships are fundamental to pharmacology and many other fields. Increasingly, scientists are encountering polytonic dose response relationships. These relationships are not well-characterized by linear and s-shaped models. Our team has extended the traditional 4 parameter logistic model by replacing the dose parameter with the quadratic function as an effective dose function. Th ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  2. Passive Pneumatic Prosthetic Ankle with Biomimetic Response

    SBC: ADA TECHNOLOGIES, INC.            Topic: DHP16C007

    The Defense Health Program seeks to improve the lives of service members suffering below knee amputations through the development of a non-powered lower extremity prosthesis designed to restore range of motion and power generation to that of an uninjured anatomical ankle. Current passive systems are still in early stages of development and typically only address one aspect of what the Defense Heal ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  3. Electrotextile Systems for Human Signatures Monitoring

    SBC: MANTEL TECHNOLOGIES, INC.            Topic: DHA17A001

    Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  4. Medical Electro-Textile Sensor Simulation

    SBC: LR TECHNOLOGIES, Inc.            Topic: DHA17A001

    LRT proposed to design a EMF detection system using future textile materials for combat uniforms. The sensor and signal processing design will be evaluated in phase I.

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  5. Smart Morphing Moulage Medical (SM3) Training Platform

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHA17A002

    Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  6. Rapid SERS-based Detection of Sepsis and TBI Biomarkers

    SBC: Ionica Sciences, Inc            Topic: DHA17B004

    Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  7. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  8. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  9. Brain Targeting Nanoparticle for Drug Delivery in Traumatic Brain Injury

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: DHA18A001

    There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  10. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TConneX Inc.            Topic: DHP16C001

    Estimation of the primary parameters like IC 50 in traditional dose-response modelsmay fail or lead to misleading results when the observations are non-onotonic due to drugresistance or virus mutation in various biomedical lab research. The objective of this project isto develop a novel approach to assess dose response relationship, which is applicable to generalpharmacologic, toxicologic, or othe ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
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