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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a topical fixed-dose combination drug for peripheral neuropathic pain.

    SBC: WinSanTor, Inc.            Topic: NINDS

    PROJECT SUMMARY An estimated 30 million people in the United States suffer from some form of peripheral neuropathy, a condition that develops as a result of damage to the peripheral nervous system. The top two major causes of peripheral neuropathy in the US are diabetes mellitus (both T1DM and T2DM) and chemotherapeutic agents. Currently, there are no FDA-approved treatments to prevent or reverse ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Virtually Empowering Schools with Adolescent Immigrant Students (VISA-IS)

    SBC: Research, Evaluation and Social Solutions, Inc. (REESSI)            Topic: 102

    ABSTRACT VISA-IS/US GAMES The Issue: Many Hispanic youth face culturally related challenges such as discrimination, being perceived as a “threat” by White and Black Americans, having to juggle and reconcile their heritage and US cultural systems, and acculturation conflicts with parents. These cultural challenges are also related to schooling: in the US, school “success” is often defined i ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. FES-Rowing: Preventing the Secondary Conditions of Paralysis Through Vigorous Exercise

    SBC: Myolyn, LLC            Topic: NICHD

    PROJECT SUMMARY/ABSTRACT Lack of exercise is a major cause of secondary health conditions, especially for people with paralysis, for whom participation in physical activity is especially difficult. Hybrid functional electrical stimulation (H- FES) exercise enables vigorous, total body physical activity for people with paralysis. However, existing H-FES devices are neither affordable nor accessible ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Intrapartum Transabdominal Fetal Pulse Oximetry: Demonstration in Ewe Models

    SBC: Storx Technologies, Inc.            Topic: NICHD

    Project Summary Despite significant cost and clear evidence of health risks associated with Cesarean section surgeries, an unnecessarily large number of infants are delivered via Cesarean section (C- Section) surgeries. The high rate of C-section in the US, relative to globally accepted norms, and the associated additional cost and complications are in part, due to high false positive rate of intr ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. A Novel, Field-Deployable, Biomimetic Narcotics Detector for the Identification of Fentanyl and Other Synthetic Opioids

    SBC: SEACOAST SCIENCE, INC.            Topic: NIDA

    AbstractThe alarming scope of the rapidly growing opioid epidemic has commanded the nation’s attention. The White House’s Council of Economic Advisers estimates that in 2015, the economic cost of the opioid crisis was over $504.0 billion (2.8% of GDP); and it is only expected to continue rising. Today, 1 in 5 fatalities amongst young adults is opioid related; with half a million fatal overdose ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Developing and Testing the Opioid Rapid Response System

    SBC: REAL PREVENTION LLC            Topic: NIDA

    The goal of this project is to prevent deaths from opioid overdoses through developing and commercializing the Opioid Rapid Response System (ORRS). This system is designed to reduce the cost of the opioid epidemic by developing standardized and effective procedures for recruiting and training citizen responders to use the PulsePoint app to administer life-saving naloxone/Narcan. This i-Corps suppl ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. STING Activators as Therapy for Cancer

    SBC: STINGINN, LLC            Topic: 101

    PROJECT SUMMARY The ability of dying cells to activate antigen presenting cells (APCs) is carefully controlled to avoid unwarranted inflammatory responses. Thus, tumor cells avoid aggravating APCs by efficiently simulating regular dying cells which following phagocytosis do not trigger inflammatory responses required for efficient cytotoxic T lymphocyte (CTL) priming. However, dying tumor cells co ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Efficacy of a novel small-molecule splicing modulator in chronic lymphocytic leukemia (CLL)

    SBC: Wildflower Biopharma Inc            Topic: 102

    Project Summary/Abstract Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in Western countries. Despite recent treatment advances, CLL remains incurable. In the era of emerging targeted therapies, disease progression and relapse increasingly are key challenges faced by CLL patients. Therefore, there is an ongoing need for the identification of targetable vulnerabilities in t ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Non-Invasive Imaging of Oral Cavity Cancer

    SBC: SUMMIT BIOMEDICAL IMAGING LLC            Topic: 102

    Project Summary/Abstract Counterintuitively, the incidence and societal impact of oral and oropharyngeal cancer are increasing in the US despite the markedly decreased use of tobacco products. This trend is exacerbated by the fact that almost two- thirds of patients have lymph node or distant metastases at the time of diagnosis, dramatically reducing 5-year survival rates. Oral cavity cancers are ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Image Analysis Tools for mpMRI Prostate Cancer Diagnosis Using PI-RADS

    SBC: Eigen Health Services LLC            Topic: 102

    Project Summary Prostate cancer is one of the most commonly occurring forms of cancer, accounting for 21% of all cancer in men. The Prostate Imaging Reporting and Data System (PI-RADS) aims to standardize reporting of prostate cancer using multi-parametric magnetic resonance imaging (mpMRI). However, the in-depth analysis, as demanded by PI-RADS, remains challenging due to the complexity and heter ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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