Award Data

This STTR Phase I project proposes to develop and establish a novel clumping (flocculation) strain of algal using an engineered extracellar protein that can be induced. The overarching goal is to provide the industry with a novel, energy efficient, and cost effective tool to dewater microalgae. What are the broader/commercial impacts of the proposed project? The broader/commercial impact of the p ...

This proposal is to develop a Handoff Training for Combat Casualty Care (HTC3) Framework.Training is the crux of the handoff problem today. Patient handoffs are a crucial part of casualty care, both in military and civilian environments; and today handoffs are being performed in less than optimal fashion, with ineffective communications accounting for 80% of the handoff errors. Our new HTC3 Framew ...

In the setting of altitude-induced hypoxia, operator cognitive capacity degrades and can compromise both individual and team performance. This degradation is linked to falling brain energy (ATP) levels and an increased reliance on anaerobic energy production from glucose. Ketone bodies are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies have sho ...

Acclimatization is the long-term adjustment that humans experience when exposed for weeks or months to high altitude. Acclimatization is important in this context because a warfighter who is acclimatized to high altitude is immune to high altitude illness, has superior work capacity, and has cognitive function approaching that found at sea level. In other words, the acclimatized warfighter is opti ...

Defense Health Agency (DHA) is seeking a multi-functional diagnostic to determine blood coagulopathy in real time at point-of-care (POC). Blood coagulopathy, resulting in uncontrolled bleeding, is implicated in 80% of operating room deaths and 50% of trau

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

The broader impact / commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable electrification of remote oil & gas processes to reduce methane emissions, improve on-site safety, and provide leak-detection and monitoring capabilities. This will be achieved by developing a robust, efficient, small-scale power generator capable of converting on-site fuel to e ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a widely applicable, innovative pipeline for drug discovery against rare genetic disorders. While each orphan disease affects a small fraction of individuals, thousands exist, affecting 400 million people world-wide. The challenge to bring therapies to the clinics for diseases th ...

The broader impact/commercial impact of this Small Business Technology Transfer Research (STTR) project is to reduce the environmental impact of agricultural production while optimizing net income to producers. Over-application of nitrogen fertilizer contributes to groundwater contamination via nitrate-nitrogen leaching, and puts substantial financial burden on rural municipalities and private wel ...

This Small Business Technology Transfer (STTR) Phase I project proposes to engineer butanol tolerance in the yeast Saccharomyces cerevisiae using a novel combinatorial genetic technology designed to enable yield enhancements in microbial production organisms. Microbial production of renewable fuels and chemicals is rapidly expanding. However, toxic products or by-products and engrained metabolic f ...