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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A cost-effective bioreactor to advance functional tissue engineering of cartilage
SBC: Apex Biomedical Company, LLC Topic: NIAMSDESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
AHTP-comet: development of an automated, high throughput comet assay system
SBC: ENGINEERING RESOURCES GROUP INC Topic: NIEHSPROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Mobile/Web-based Training Curriculum for Disseminating Best Practices for the Care of Newborns with Neonatal Opioid Withdrawal Syndrome
SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC. Topic: NIDAAbstractThe incidence of neonatal opioid withdrawal syndrome (NOWS) in the United States has grown dramatically over the past two decades. Efficient and effective resources and materials for training neonatal care providers in empirically based practices for NOWS are greatly needed. The goal of the proposed Phase I STTR project is to develop a highly accessible mobile/web-based multimedia curricul ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
An Advanced Lung Organomimetic to Reproduce Human Airway Pathophysiology
SBC: PNEUMAX, LLC Topic: 113PROJECT SUMMARYThree of top five causes of death in humans globally are lung relatedchronic obstructive pulmonary diseaseCOPDlower respiratory infections and lung cancers collectively account for over eight million deaths annuallyCurrentlyin preclinical settingstatic cell cultures and animal models are the most widely used systems for mechanistic and translational studiesHowevercritical limitation ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A new generation, enhanced, corneal-birefringence-independent retinalscanning device for pediatric vision disorders using polarization modulation
SBC: REBISCAN, Inc. Topic: NProject Summary/Abstract !Amblyopia is vision loss caused by neglect of a structurally normal eye due to strabismus, asymmetric refraction (anisometropia), or deprivation. It is irreversible if not treated by age 7, but half of all patients in the U.S. are undetected and untreated until after it is too late, making it the leading cause of preventable vision loss. Rebion (Rebiscan, Inc) has develop ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A novel device for cervical insufficiency in pregnant women
SBC: Cx Therapeutics, Inc Topic: NICHDAbstract In normal pregnancy, the cervix remains closed until term and then dilates under the influence of uterine contractions. In cases of cervical insufficiency (CI), the cervix dilates in the second trimester in the absence of uterine contractions, which leads to a preterm birth. Infants born prematurely are at risk of lifelong morbidities including chronic lung disease, feeding difficulties, ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A Novel Insulin Pathway Agonist for Alzheimer's Disease
SBC: MEDCHEM PARTNERS LLC Topic: NIADESCRIPTION (provided by applicant): Even though the association of -amyloid peptide (A ) deposition and Alzheimer's Disease (AD) underpins the major hypothesis for disease progression and possibly causation and several drugs addressing the formation or removal of -amyloid plaques have entered clinical trials, no effective therapy exists to date for AD. This reality calls for new targets th ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
Antimetabolites for Acute Myeloid Leukemias
SBC: Quercus Molecular Design, LLC Topic: 100Abstract: Hematological malignancies, specifically leukemias, are cancers affecting various types of blood cells. They are among the most common cancers worldwide and account for more than 10% of all new cancer diagnoses. One particularly challenging form of leukemia is Acute Myelogenous Leukemia (AML), which is the most common form of adult leukemia. AML is still very difficult to treat and typic ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A Portable Device for Accurate Mouse Tail Vein Injection
SBC: Technology Commercialization Partners LLC Topic: ODPROJECT SUMMARYABSTRACT To datethe standard method to access a mouse tail vein is manual injectionbut its yield rate is poor in generalThis leads to multiple needle insertions associated with tissue damage and painBesidesfailure in tail vein injection leads to data lossand thereby more animals will be required to compensate itFinallythe dose variation induced by unreliable injection increases erro ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Small Molecule to Activate Tumor Immunity after PLX403 in V600E BRAF Melanoma
SBC: ARISAPH PHARMACEUTICALS, INC. Topic: NCIDESCRIPTION (provided by applicant): In the United States, around 76,250 new cases of melanoma and 9,180 melanoma-related deaths are predicted for 2012. With the therapeutic options currently available, metastatic melanoma patients face the bleak prospectof at best, 10 month's survival and a one-in-ten chance of surviving for 10 years. Surgery and radiation therapy are the mainstay of treatme ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health