Award Data

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

The objective of this proposal is to examine the feasibility of defining and measuring key dimensions of an urban system to include its essential functions and networks, and whether they can be modelled in a computational framework for assessing robustness and resilience of DUTs (and their tipping points) under conditions of volatility and stress. This proposal will conduct a comprehensive review ...

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

ABSTRACT: In this Phase I STTR project, we propose to demonstrate the feasibility of developing a low cost, compact, time-domain terahertz (TD-THz) spectrometer specifically for the characterization of semiconductor materials over a range of temperatures, electric fields, and magnetic fields. In phase I, we will configure fiber optic coupled TD-THz instrumentation to make measurements on a sampl ...

Approximately 5-6% of military injuries involve some form of major peripheral nerve injury with little chance of spontaneous healing. Currently these injuries lead to major impairment of voluntary muscle function in the limbs and extremities, making tasks of walking, reaching, grasping, etc. very difficult or impossible for many patients. It is not enough to focus therapeutic treatment on the se ...

NDI of composite Pi/T-Joints presents significant challenges to existing inspection technologies resulting in a barrier to implementation in production. We will investigate feasibility of developing an active thermography NDI solution for real-world inspection of composite structures with T / Pi- joints during the manufacturing process (both green and cured states). Based on the extensive experien ...

Palm-sized unmanned aerial systems (nano UAS) weighing tens of grams have evolved to the point where they are becoming useful to the warfighter. However, their small mass, fragility, and limited batteries still necessitate the use of emerging, low mass/power technologies to meet the full range of potential missions, including new autonomous flight control and collision avoidance strategies, struct ...

Navitas will collaborate with the University of Maryland group to develop a flexible microporous Li metal anode. The proposed porous anode will reduce Li dendrite growth via its built-in porosity and increase rate capability via its high surface area. It will enable a conformal, safe, and light weight lithium metal batteries as soldier portable power devices. The Phase I project will demonstrate t ...

ABSTRACT: Ultra-high performance concrete (UHPC) materials with outstanding material properties offer significant promise to transform infrastructure design and service life. Evolution of UHPC into a mainstream construction material would benefit from the resolution of issues relevant to the restrictive selections of finer aggregates/fillers, large heat of hydration and thermal stresses, high aut ...

ABSTRACT: Feature extraction and target recognition suffer from a lack of a reliable model for both exploitable target features and the electromagnetic signature they possess. Signature data are often hard to interpret and invert to recover the target robustly. Bayesian learning approaches to statistical pattern recognition are based on the use of training sets of inputs and outputs, a data mode ...