Award Data

The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

Built upon the progress in Phase I period, Winchester Technologies, LLC is pleased to propose to investigate practical magnetoelectric antennas during the Phase II period based on solidly mounted resonators (SMR), which will have enormous impacts on DoD and civilian antenna applications. State of the art antennas suffer from three major open challenges: (1) large antenna size > ?0/10, (2) antenna ...

Physical Sciences Inc., in cooperation with University of Notre Dame, will develop a method for the persistent detection of aerosolized biological warfare agents using a distributed and cooperative sensor network within a Bayesian framework. The proposed system, named BioNet, will provide a wider coverage and two-fold reduction in false alarm rate over individual sensor performance through intelli ...

The proposed SBIR program will employ Physical Sciences Inc.’s (PSI) unique ground-based high altitude plume signature simulation facility to examine the interactions of hyperthermal oxygen atoms with specific plume constituents believed to contribute to plume emission in the ultraviolet and visible spectral regions. These reactions will include the multi-step O + CH4 reaction predicted to produ ...

Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

Physical Sciences, Inc. and Colorado State University will advance the technical maturity of the Compressive Sensing Hyperspectral Imager (CS-HSI) platform. The CS-HSI operates in the longwave infrared (LWIR) spectral range with a single-pixel architecture for low-cost, standoff wide area Early Warning of chemical vapor plumes. The motivation for applying CS to LWIR HSI is to eliminate the high-co ...

Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders as the first line of defense for personnel working in contaminated environments. Many innovative products have been developed for the chemical protective clothing market in response to demand from the market place for improved performance. However, the need for ...

The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and 2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survival rates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ...

Physical Sciences Inc. will develop a Tomographic Digital Holographic Microscope with integrated Infrared spectromicroscopy (T-DHM/IR) to enable time resolved correlation of chemical and 3D structural properties of biological warfare agents (BWAs), microorganisms and infected human tissue. The T-DHM/IR uses a precision hexapod stage and a custom reflective microscope objective with NA = 0.83 to pe ...

Military respirator masks provide the Warfighter with life critical protection against chemical, biological, radiological, and nuclear (CBRN) threats. To ensure the safety, comfort, and effectiveness of the American Warfighter, it is essential that every Warfighter be assigned a respirator that is properly sized and fitted. However, current methods for sizing and fitting respirators depend on manu ...