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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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KAPS Biotech: A novel biomarker to improve prostate cancer diagnosis
SBC: KAPS BIOTECHNOLOGY LLC Topic: 102Abstract Prostate cancer (CaP) is the most common non-skin cancer in men and third most common cause of cancer deaths in men. Black men experience a higher burden of incidence and mortality from CaP compared to White men. The Prostate-Specific Antigen (PSA) test, a commonly used biomarker for early diagnosis and management of CaP, cannot alone accurately predict the presence of CaP, its aggressive ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement
SBC: POLYNOVA CARDIOVASCULAR INC Topic: NHLBIProject Summary: A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacement (TAVR) has emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosis (AS). Recent longitudinal follow-up studies of TAVR patients however indicate that this procedure and associated technology may result i ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A Mobile/Web-based Training Curriculum for Disseminating Best Practices for the Care of Newborns with Neonatal Opioid Withdrawal Syndrome
SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC. Topic: NIDAAbstractThe incidence of neonatal opioid withdrawal syndrome (NOWS) in the United States has grown dramatically over the past two decades. Efficient and effective resources and materials for training neonatal care providers in empirically based practices for NOWS are greatly needed. The goal of the proposed Phase I STTR project is to develop a highly accessible mobile/web-based multimedia curricul ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
An adjuvanted influenza vaccine platform for dose sparing, multiplexing, and rapid deployment
SBC: POP Biotechnologies Inc. Topic: NIAIDAbstract Influenza is the cause of considerable morbidity and mortality globally. Certain groups, i.e., infants, pregnant young women, and older adults are especially at risk for severe disease. Despite immunization being the most effective and economical prophylactic approach, vaccines often provide less than optimal defense against an influenza illness, with efficacies ranging from 10-60%. This ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Optimizing a Stapled-Peptide That Specifically Targets HSV-1 to Treat Herpes Ocular Keratitis
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NEIABSTRACT Infection of the eye by Herpes Simplex Virus-1 (HSV-1) can result in Herpes Keratitis (HK), which is the leading cause of corneal blindness worldwide. Ocular herpes infections are often recurrent and culminate in progressive corneal scarring and loss of vision. The gold standard treatment is Acyclovir (ACV) that targets HSV-1 thymidine kinase (TK). Although ACV is highly effective against ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Next-generation precision medicine for targeting recombination-deficient cancers
SBC: RECOMBINATION THERAPEUTICS LLC Topic: OPrecision medicine is a revolutionary therapeutic approach in which therapies are designed and selected based on genetic mutations present in certain cancers. For example, treating patients with BRCA-deficient cancers with a medicine that inhibits a particular DNA repair pathway can result in selective killing of these cancer cells. This approach is based upon the concept of synthetic lethality wh ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Portable, affordable, quantitative microchip electrophoresis system for integrated anemia and hemoglobin variant testing
SBC: HEMEX HEALTH INC Topic: NHLBIPROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has high prevalence affecting over one-third of the worldandapos;s population or about 2.5 billion people. Anemia has numerous causes, including nutritional deficiencies, oncologic conditions, and hematologic diseases, including hemoglobin gene variants. More than 7% of the worldandapos;s population carry hemoglobin gene va ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Hemoglobin-based antidotes for the treatment of carbon monoxide poisoning
SBC: GLOBIN SOLUTIONS INC Topic: NIEHSProject Summary/AbstractCarbon monoxide (CO) poisoning remains a major cause of death and disability, affecting 50,000 persons a year in the U.S. alone. Victims removed from fires or rescued after exposure to car or home generator exhaust only have two options: 100% oxygen or transfer via ambulance or medical evacuation helicopter to a specialized facility with emergency hyperbaric oxygen chamber. ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Clinical Text Automatic De-Identification to Support Large Scale Data Reuse and Sharing
SBC: Clinacuity, Inc Topic: 400The adoption of Electronic Health Record (EHR) systems is growing at a fast pace in the U.S., and this growth results in very large quantities of patient clinical data becoming available in electronic format with tremendous potential but an equally large concern for patient confidentiality breaches. Secondary use of clinical data is essential to fulfill the potential for high quality healthcare, i ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Evaluation of a peptide that inhibitsthe activation of NOX2 and the generation of reactive oxygen species in protection against acute lung injury
SBC: Peroxitech LLC Topic: NHLBISUMMARY: Acute lung injury (ALI) is a devastating complication of sepsis,viral and bacterial pneumonias, severe trauma with or without major blood loss, acid aspiration and other conditions that affect the lung either primarily or secondarily.This relatively common syndrome (~200,000 cases per yr in the US) currently has an overall mortality rate of ~40%. Lung inflammation associated with the prod ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health