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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.
SBC: ARCHER PHARMACEUTICALS, INC. Topic: NIAPathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment
SBC: APPLIED UNIVERSAL DYNAMICS, CORP Topic: NIAProject Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Technology for the non-invasive surveilance of post-traumatic compartment syndrome
SBC: MYOLEX, INC. Topic: NIAMSPROJECT SUMMARYAcute compartment syndromeACSremains one of the most devastating and often overlooked traumatic musculoskeletal disorders in clinical practiceIn this conditionpressure increases in one of the body s spacelimited compartmentsdue most commonly to direct trauma or bone fractureresulting ultimately in an ischemic injury to all of the compartment s contentsincluding muscle and nerveOnce ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Bitter Human Taste Bud Epithelial Cell Platforms for Bitter Taste Antagonist Discovery
SBC: DISCOVERYBIOMED, INC. Topic: NIDCDPrincipal Investigators for Small BusinessDiscoveryBioMedIncDBMand Monell Chemical Senses Center Project Summary Abstract Bitter taste in foods and medicines presents a barrier to overcoming global public health challengesfood insecuritypoor nutritional healthand poor compliance with medication useparticularly among children and the elderlySugar and saltthe mainstays to address these challengesfur ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Evaluating Synthetic Biology Produced Triterpene Oils in Adjuvant Formulations
SBC: Enepret Incorporated Topic: NIAIDABSTRACT Vaccine adjuvants help stimulate the body to generate an immune response when co injected with an antigenthe compound for which immunity is desiredAlthough the human body is capable of producing antibodies to most injected antigensadjuvants can help boost the body s ability to mount a successful and acquired immune response to the presented targetAdjuvants have been shown to enhance immun ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Validation of Novel Therapeutic Approach for Leptomeningeal Metastases
SBC: Minnetronix Medical, Inc. Topic: 102ABSTRACT Leptomeningeal Metastases (LM) is a condition in which tumor cells from a primary tumor metastasize, invade the subarachnoid space (SAS) and spread throughout the cerebrospinal fluid (CSF), resulting in seeding along the meninges, brain and spinal cord. LM represents a devastating event of cancer progression. There are 30,000 cases annually and currently no cure, with average survival of ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of mitochondrial disease mouse models
SBC: B-MoGen Biotechnologies Inc Topic: ODProject Abstract Mitochondria are double membrane bound organelles that are found in all eukaryotic cells and carry a specialized circularkb genomeThere is a group of devastating human genetic diseases caused by inherited or spontaneous mutation of genes encoded within the mitochondrial genomeThese diseases can cause a wide array of medical problems from subtle muscular weakness to extreme neuromu ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Cell-free protein synthesis (CFPS) devices with high-yield for synthetic biology
SBC: DASFANH BIOSCIENCES, LLC Topic: 400Project SummaryCell free protein synthesisCFPSis a method of producing proteins outside living cells and has distinct advantages over traditional cell culture based protein productionIt is often difficult to maintain complex environmental condition for cell viability and the subsequent need to develop a downstream process for purification of product in traditional cell based systemsCFPSon the othe ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Create Ultralong DNA Constructs in One Assembly Step
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: 400Create Ultralong DNA Constructs in One Assembly Step Firebird Biomolecular Sciences LLCSteven ABenner Foundation for Applied Molecular EvolutionShuichi Hoshika AbstractFrost andampSullivan found aglobal market for DNA oligos at $million$million for genesPrivate investment in DNA synthesis companies like TwistGinkgoand DNA Script give collective valuations of several billion dollarsFederal public i ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Portable, affordable, quantitative microchip electrophoresis for hemoglobin A1C testing
SBC: HEMEX HEALTH INC Topic: NIDDKPROJECT SUMMARY Diabetes is one of the most important health issues in the worldIt is a disease that disproportionately affects low and middle income countriesNot only is diabetes a major cause of morbidity and mortalityit can devastate the finances of families and strain countriesfinancial resourcesKey components for addressing this healthcare crises include early diagnosis as well as ongoing mon ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health