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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Wavelength-Agile Real Time Tabletop X-ray Nanoscope based on High Harmonic Beams

    SBC: Kapteyn-Murnane Laboratories, Inc.            Topic: ST15C001

    Nanoscale, material sensitive, imaging techniques are critical for progress in many disciplines as we learn to master science and technology at the smallest dimensions — on the nanometer to atomic-scale. However, progress in both science and technology is becoming increasingly limited by the constraints of current imaging techniques and metrologies. Fortunately, by combining coherent extreme UV ...

    STTR Phase II 2019 Department of DefenseDefense Advanced Research Projects Agency
  2. Metal Digital Direct Manufacturing (MDDM) for Close-Out of Combustion Chambers and Nozzle Fabrications

    SBC: Keystone Synergistic Enterprises, LLC            Topic: T12

    This NASA sponsored STTR project will investigate methods for close-out of large, liquid rocket engine, nickel or stainless steel nozzle, coolant channels utilizing robotic laser and pulsed-arc additive manufacturing (AM)methods. Structural jacket to coolant channel land area interface strength will be quantified and metallurgical characterization completed.Process optimizations will be conducted ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  3. Highly Sensitive Flash LADAR Camera

    SBC: VOXTEL, INC.            Topic: T9

    To address the urgent need for 3D flash-lidar technology for landing on solar system bodies and for spacecraft rendezvous and docking with satellites, an effort is proposed to fabricate, characterize, and test a versatile, high-sensitivity InGaAs APD 3D flash lidar and to advance the technology-readiness level (TRL) of lidar technologies suitable for NASA mission requirements. Leveraging an existi ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  4. Rapid Discovery of Evasive Satellite Behaviors

    SBC: Data Fusion & Neural Networks, LLC            Topic: AF17CT02

    The problem addressed in this effort is to automatically learn historical ephemeris space catalog time, position, and velocity entity track update error uncertainties (i.e., without track error covariances) and to automatically (e.g., without expert event labeling) produce: – unmodeled non-gravitational space catalog update flags – abnormal unmodeled catalog update flags with abnorma ...

    STTR Phase II 2019 Department of DefenseAir Force
  5. STTR Phase II: Deep Learning Technology For The Microscopic Analysis Of Stained Cells Using Unbiased Methods

    SBC: Stereology Resource Center, Inc            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of software to help bioscientists analyze more tissue in less time and with higher accuracy and reproducibility. Currently, stereology studies require a trained technician to sit before a computer screen, making tedious manual counts (clicks) on hundreds to thousands of mic ...

    STTR Phase II 2019 National Science Foundation
  6. In Vivo Studies of a Novel HDAC Inhibitor for Treating Hemoglobin Disorders

    SBC: Cetya Therapeutics, Inc.            Topic: NHLBI

    PROJECT SUMMARY The β-hemoglobinopathies are prevalent genetic blood diseases with few treatment options. It is estimate that 7% of the worldandapos;s population carries an abnormal hemoglobin gene with 400,000 infants born annually with a severe life threatening hemoglobinopathy. Drug mediated induction of normal, but developmentally silenced, fetal hemoglobin (HbF) expression reduces anemia and ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke.

    SBC: BIOMIMETIX JV LLC            Topic: 102

    Ischemic stroke is a leading cause of death and disability in the United States. This often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolism. Patients who present within 4.5 hours of symptom onset are eligible for thrombolysis with tissue plasminogen activator (tPA). This serves andlt;5% of victims. Recently, major advance has been made with proven efficacy fro ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Targeting glioblastoma stem-like cells with custom-designed viral vectors

    SBC: Lacerta Therapeutics, Inc.            Topic: 102

    Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Volume Digital Holographic Wavefront Sensor Phase 2

    SBC: NUTRONICS, INC.            Topic: AF18AT006

    Through the execution of our Phase 1 effort, Nutronics, Inc. and Montana State University developed an improved means to optimize the Pellizzarri cost functional for coherent imaging using digital holography. Our algorithm developed during the Phase 1 effort accelerates convergence times by a factor of 20-40 for the majority of scenarios evaluated. Our proposed Phase 2 effort has a two-fold focus: ...

    STTR Phase II 2019 Department of DefenseAir Force
  10. Full Mueller Matrix Characterization of Imaged Samples using Digital Holography

    SBC: Polaris Sensor Technologies, Inc.            Topic: AF18AT007

    The Phase II effort will be to clearly demonstrate the feasibility and build a prototype of a noncontact, high-quality holographic polarimetry system with pixel level depth and Mueller matrix information with a user-friendly interface to image and display this data. The measurements of each data product will be validated with trusted truth samples. The system will be reproducible and will have a d ...

    STTR Phase II 2019 Department of DefenseAir Force
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