Award Data

The scope of this research initiative addresses what is best practice for delivering mobile applications while ensuring a safe, consistent experience given the differing communications standards, operating systems and hardware limitations of existing and prospective personal communications devices.  It is assumed the scope of this initiative is limited to exploration of applications for consumer devices only, not on-board OEM equipment/applications that may use a passenger's personal communications device to provide network connectivity.  However, the ability of a personal device

This SBIR Phase-I project is to develop an acoustic CMP (Chemical Mechanical Polishing) slurry monitor?a fully in-line, real-time, point of use instrument that will detect and disperse any and all large agglomerates in the nanofine slurries used in IC manufacture. Left unchecked, these errant slurry particles/ agglomerates can "kill" (deeply scratch) a semiconductor wafer as it undergoes chemical ...

DESCRIPTION (provided by applicant): New approaches are needed to improve the treatment options of over 50 million people in the United States suffering from chronic pain. The proposed research is designed to develop a novel class of opioid analgesicsthat produce less tolerance and may potentially reduce opiate-associated side effects. Opioid ligands activate G protein coupled receptors (GPCR) ...

This Small Business Technology Transfer Phase 2 effort focuses on development of a supercapacitor energy storage device based on novel metal oxide-carbon nanocomposites. In the Phase 1 project, NanoScale discovered a group of cathode nanocomposites with an exceptionally high capacitance of 270 F/g and a large potential window of 3.8 V versus metallic lithium in inorganic electrolytes. The combinat ...

DESCRIPTION (provided by applicant): Within the last seven years, Drosophila melanogaster or common fruit fly has gained an important niche in becoming an invertebrate model organism for exploring genetic and proteomic mechanisms underlying sleep. While agreat deal of progress has been made in the field of Drosophila sleep research using available tools, they are limited for the observation, recor ...

The goal of the project is to develop a rapid in vitro screening assay for detection of cancer biomarkers in urine and blood. The aim is testing and optimization of nanoparticle sensors, based on cyanine dyes that are chemically linked to Fe/Fe3O4 nanoparticles via protease-selective consensus (cleavage) sequences. The focus is on the quantitative determination of active cancer-specific proteases ...

The function of many cancer related proteins is modulated by modifications such as phosphorylation and glycosylation. The development of antibodies that recognize site-specific phosphorylation has vastly improved our understanding of signal transductionand cancer cell physiology and regulation. However, almost no available antibodies recognize site specific glycosylation, and in particular, N-a ...

Under Phase I of this SBIR Fast-track project, a base manufacturing process to produce a reliable, robust ethanol biosensor will be developed and the feasibility of the biosensor, capable of real-time monitoring of ethanol, will be demonstrated and a functional prototype ethanol biosensor will be delivered. During Phase II, the biosensor design prototype and multi-sensor array (a three-channel ...

The DoEs Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) pursues accurate measurements of atmospheric radiation through its Aerial Vehicle Program (AVP). The ability to measure atmospheric radiation while in flight is a valuable capability for atmospheric research. These measurements complement satellite and ground station measurements in providing increased certainty in v ...

Recent advances in directed energy weapons (DEW) require radar systems to implement front door protection against high power signals. Although nonlinear protection elements have been successfully employed in the past, fast ultra wideband (UWB) and high power microwave (HPM) signals are not successfully blocked by most current circuit protection technologies. This proposal details the develop ...