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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. A device containing an immobilized chelator to remove aluminum from total parente

    SBC: ALKYMOS, INC            Topic: NICHD

    DESCRIPTION (provided by applicant): A high percentage of the ~ 500,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common contam ...

    STTR Phase II 2010 Department of Health and Human Services
  2. A non-surgical embryo transfer device for producing gene modified rats

    SBC: PARATECHS CORP.            Topic: NCRR

    DESCRIPTION (provided by applicant): Rats represent the most commonly used physiologically and pharmacological experimental model for studying human disease. The ability to genetically modify rats through methods of gene transfer in fertilized rat embryos or by gene targeting in embryonic stem (ES) cells has significantly increased the capabilities of rats in biomedical and pharmaceutical research ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Accelerated Learning for Cyber Insider Threat Reduction (XL-CITR)

    SBC: Tier 1 Performance Solutions, LLC            Topic: OSD08CR8

    Future U.S. Information Systems will be subject to increased attacks. These attacks will come from both internal and external threats. As reflected by the budgets for combating these threats, external cyber threats are assumed to be more likely. By comparison, internal threats to cyber networks from U.S. personnel receive little attention; yet, the consequences can be even more devastating. Al ...

    SBIR Phase II 2010 Department of DefenseAir Force
  4. ApoFasL as a novel treatment for Type 1 Diabetes in Nonhuman Primates

    SBC: APOIMMUNE, INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Pancreatic islet transplantation is a viable approach for the treatment of type 1 diabetes (T1D). However, this therapeutic approach suffers from graft rejection. Dr. Shirwan, founder of ApoImmune, has developed a novel immunotherapeutic approach aimed at tolerance induction to alloantigens without chronic use of general immunosuppression. This approach, terme ...

    STTR Phase I 2010 Department of Health and Human Services
  5. Automated Tool for Assessing Usability in Systems (A-TAUS)

    SBC: Tier 1 Performance Solutions, LLC            Topic: HSB0102005

    In this proposal, TiER1 Performance Solutions and Alion Science and Technology offer to develop A-TAUS (Automated Tool for Assessing Usability in Systems) to assist DHS engineers in improving usability without the burden of learning numerous disconnected tools. A primary goal of Phase I is to develop a proof-of-concept prototype that includes a research-based organizing framework for analyzing usa ...

    SBIR Phase I 2010 Department of Homeland Security
  6. Commercialization of a Diagnostic Test for Alzheimer's Disease

    SBC: SCOUT DIAGNOSTICS            Topic: NIA

    DESCRIPTION (provided by applicant): The major barriers to preventing or treating Alzheimer's disease (AD) are its unknown pathogenesis/etiology and the lack of an objective, sensitive and specific biomarker of the disease, particularly at the early stages when therapeutic interventions would likely have the greatest efficacy. The basic hypothesis of this project is that levels of a unique high mo ...

    STTR Phase II 2010 Department of Health and Human Services
  7. Concurrent Upper/Lower Extremity SCI Exercise with Stimulation

    SBC: CUSTOMKYNETICS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): This proposal will develop a FES-augmented recumbent stepper that elicits lower extremity involvement through electrical stimulation while upper extremity involvement is volitionally controlled by the client. Exercise for people with spinal cord injury not only enhances physical fitness but has the potential to slow or reverse many of the secondary complication ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Counterpulsation Device with Integrated ECG Sensing

    SBC: SCR, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Counterpulsation with an intra-aortic balloon pump has been widely and successfully used as a short term treatment for both acute and chronic cardiac dysfunction. SCR (Louisville, KY) is developing a novel chronic, implantable counterpulsation device (CPD) to treat late stage HF patients. The CPD is a 32-ml stroke volume polyurethane-lined blood chamber design ...

    SBIR Phase I 2010 Department of Health and Human Services
  9. Creation of hyperactive transposons for mutagenesis in rodents


    DESCRIPTION (provided by applicant): The rat is a favored model for many types of human disease for which mice are not suitable. As opposed to the mouse, rats and humans also share more similarity in their cytochrome P450 genes, making the rat a more useful model for toxicology and pharmacology studies. The rat is also a favored model for diabetes, arthritis, behavioral disorders (including drug a ...

    SBIR Phase II 2010 Department of Health and Human Services
  10. Deep Submergence Rated Flexible Hoses and Piping System Connectors

    SBC: ATKINS & PEARCE, INC.            Topic: SOCOM08002

    There are many commercially available flexible hoses for use in non-rigid coupling of hydraulic, air, and other piping systems. However, these systems are currently not designed for operating under severe hydrostatic and dynamic pressures experienced by Deep Submergence Systems in their extreme operating environments. The pipes that connect the DDS to the sub are exposed to the water and experien ...

    SBIR Phase II 2010 Department of DefenseSpecial Operations Command

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