Award Data

DESCRIPTION (provided by applicant): The Applicant proposes an improvement to monoclonal antibody technology through the generation of transgenic mice engineered to facilitate flow cytometric isolation and cloning of specific antigen-reactive plasmacytes. Monoclonal antibodies (mAbs) are arguably the most important biological reagents used in biomedical research, diagnostics, and therapeutics, and ...

This SBIR project aims at the development of an innovative technology that can be attached to existing submerged arc welding (SAW) systems to monitor and feedback control the depth of weld penetration. Existing SAW systems will be operated using existing welding procedures without modifications. In many applications skilled welders may adjust the welding parameters based on their observation of dy ...

The DoD spends over $1 Billion annually on disability payments attributed to hearing loss, yet this can be prevented. Research shows that with proper hearing protection a 19% reduction in hearing loss cases can be expected. Custom ear plugs force the user to wear the devices correctly and to retain hearing protection during activity, thus eliminating improper seating issues as the primary cause of ...

The aluminum alloys have low density, relatively high strength, and high strength-to-weight ratio, which brings some major advantages in marine structure design, fabrication, and operations. However, marine ships are subjected to a complex and severe loading, and the typical failure mode of aluminum under extreme dynamics loading such as wave slamming and high velocity impact is ductile fracture. ...

Research is proposed for the development and implementation of state of the art computational and experimental tools for the investigation of the impact of control surface freeplay on the flutter and limit cycle oscillation characteristics of two-dimensional and three-dimensional wings in subsonic and transonic flow. Highly efficient and accurate aeroelastic simulation tools will be constructed ba ...

This Small Business Technology Transfer Phase I project is aiming at developing and implementing a multiscale composite model to predict the ceramic matrix composite (CMC) response to the impact loading by foreign objects. In particular, the physics-based model will be applied to describe the multiscale foreign object damage (FOD) phenomena of CMCs due to the complex nature of impact dynamics coup ...

Turbine disks are amongst the most critical components in aero- and naval-vessel engines. They operate in a high pressure and temperature environment requiring demanding properties. Nickel-based supperalloys which have high creep and oxidation resistance at high temperatures are widely used as the material of turbine disks. The elevated-temperature strength of this supperalloy and its resistance t ...

Research is proposed for the development and implementation of state of the art, reduced order models for problems in nonlinear aeroelasticity. Highly efficient and accurate aeroelastic simulation tools will be constructed based upon the mathematical formalism of optimal prediction theory and a novel implementation of a filtered harmonic balance solution methodology. The implications of the propos ...

The design, development, testing, and maintenance of future complex combat systems will require new approaches and technologies. Present software technologies are limited by the fact that the computing system architectural layers and software components are not integrated. New software technologies are needed to adopt a more integrated view of the system architectural layers and software component ...

The proposing team will continue the development and testing of the Autonomous UAS Detect, Sense, and Avoid (AU-DSA) system for Unmanned Aerial Systems (UAS). Key capabilities of the AU-DSA that set it apart from other autonomous collision avoidance systems include: 1) Autonomously complying with federally mandated operating procedures, 2) Operating as efficiently in multiple-aircraft scenarios as ...