Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Whole Mouse Cryo-Imaging

    SBC: BIOINVISION INC.            Topic: N/A

    DESCRIPTION (provided by applicant): BioInVision, Inc. and Case Western Reserve University researchers will develop a cryo-imaging system for 3D imaging of mice. It will serve very many applications in biological research and the biotechnology industry, in cluding mouse anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, pathogen/immune system response, and stem cells/regene ...

    STTR Phase II 2008 Department of Health and Human Services
  2. Finding Strength in Culture: A Video Series for American Indian Parents

    SBC: InterVision Media            Topic: N/A

    DESCRIPTION (provided by applicant): Over five hundred years of contact with European culture has had a profound impact on American Indian communities, with destructive policies implemented in the service of assimilation efforts that broke up the extended family and community. The strains of history pressing on American Indian families are reflected in research indicating weakened family connecti ...

    STTR Phase I 2008 Department of Health and Human Services
  3. Web-Based Respiratory Education About Tobacco and Health

    SBC: InterVision Media            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop an interactive Internet-based program (WeBREATHe: Web-Based Respiratory Education About Tobacco and Health) to train pediatric respiratory therapists and nurses to provide brief, hospital-based tob acco cessation interventions to parents of hospitalized pediatric patients. During Phase I, we designed and evaluated a prototype program, base ...

    STTR Phase II 2008 Department of Health and Human Services
  4. Minimally-Invasive Image-Guided Therapy for Cancer Treatment

    SBC: CONTRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a technology and eventually a minimally-invasive commercial system for image-guided photodynamic therapy for cancer. This is certainly in keeping with NCI's focus o n imaging in vivo for cancer screening, diagnosis, progression, image-guide therapy, treatment monitoring, and recurrence. In studies conducted ...

    STTR Phase I 2008 Department of Health and Human Services
  5. Web-based Family Intervention for Pediatric Obesity

    SBC: DESCHUTES RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recent studies indicate that the prevalence of overweight and obesity in children is very high (about 25-30 percent), and the incidence is increasing, especially among minority African- American and Hispanic children. O besity in childhood is associated with a high risk of continued obesity into adolescence and adulthood. This is of great public health signific ...

    STTR Phase I 2008 Department of Health and Human Services
  6. Delivery system development for a reservoir targeted Lyme disease vaccine

    SBC: FoodSource Lure Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The incidence and geographic distribution of Lyme disease in the U.S. has increased steadily since its first description in 1977. Efforts to stem the spread of the disease through controlling the population of its tick vector and/or the mouse reservoirs of the disease have met with only limited success. The only approved human vaccine to protect against Lyme d ...

    STTR Phase I 2008 Department of Health and Human Services
  7. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase II 2008 Department of Health and Human Services
  8. Snapback Primers for Genotyping and Mutation Scanning

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Fast-Track STTR is to develop a simple, inexpensive, closed-tube PCR method for genotyping and sequence variant scanning. Instead of covalently-labeled probes, one of two primers includes a tail w ith a probe element. After asymmetric PCR, this tail anneals internally to the same strand, snapping back , to form a stem/loop structure. Bot ...

    STTR Phase I 2008 Department of Health and Human Services
  9. Improved Therapy of Prostate Cancer

    SBC: OAKWOOD LABORATORIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The central objective of this project is to develop a novel and most promising androgen-camptothecin- type analog with higher efficacy and lower toxicity for clinical use in chemotherapy of prostate cancer, with partic ular emphasis on improving the survival of patients with hormone-refractory prostate cancer (HRPC). A novel androgen-camptothecin analog (OL-1) ...

    STTR Phase I 2008 Department of Health and Human Services
  10. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human Services
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