Award Data

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This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel Quality-by-Design (QbD) software platform directed at the needs of FDA's QbD initiative, a framework for innovative pharmaceutical development, manufacturing and quality assurance. QbD is implemented at four levels: process understanding; quality by design; monitor, predict and control; and continuous improveme ...

This Small Business Innovation Research Phase I project developes methods to molecularly abort sorghum embryos, early in their development, to redirect nutrients, normally used for embryo development, toward starch accumulation. The research will construct and test genetic cassettes necessary for aborting embryo development in seeds and identify sorghum lines possessing high tissue culture regener ...

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This Small Business Innovation Research (SBIR) Phase I project will develop a novel hydroxyl ion-conducting polymer membrane for use in anion exchange alkaline fuel cells through a parallel approach based on two novel polymer approaches each combined with nano particle functionality. A key issue with traditional alkaline fuel cells (AFC) is electrolyte and electrode degradation caused by the formi ...

CONVENTIONAL REMOTE MANIPULATOR END-EFFECTOR TECHNIQUES ARE NOT SATIFYING THE CURRENT NEED FOR SMALLER, SIMPLER, MORE EFFICIENT MICRMANIPULATOR SYSTEMS. THERE IS CLEARLY A NEED FOR AN ENTIRELY DIIFERENT APPROACH TO GENERATING AND CONTROLLING MECHANICAL MOTION AT MILLIMETER AND SUB-MILLIMETER LEVELS. ONE SUCH APPROACH, SUGGESTED IN THIS PROPOSAL, TAKES ADVANTAGE OF THE PIEZOELECTRIC PROPERTIES OF C ...

This Small Business Innovation Research II project will develop hermetic hollow gas encapsulating spheres (Plasma-spheres) with shells fabricated from phosphor compositions processed with modified processing methods. The outcome will be blue emitting Plasma-spheres and improve red and green Plasma-spheres for use in a full color flexible plasma display. Plasma-spheres are placed on flexible electr ...

This Small Business Innovation Research (SBIR) Phase I project will demonstrate method of depositing high density and reproducible epitaxial metal oxide thin films using a spin-on deposition technique. This method is not limited to the oxides, but can be used to deposit thin films of nitrides, carbides, and sulfides as well. The project will focus mainly on process development in which only a few ...

This Small Business Innovation Research (SBIR) Phase I research project aims to develop novel nucleic acid labeling reagents that can be used in living cells to monitor gene expression. Instead of relying on labeling the molecules using fluorescently labeled bases, the proposed approach relies on adding the label to the terminal phosphates. This would have great advantage over existing methods a ...

This Small Business Innovation Research Phase I project develops a new technology for prosthetic arm components, using a lightweight piezoelectric actuator. A piezoelectric actuator will be developed to drive a prosthetic hand. Available arm prostheses have up to three powered degrees-of-freedom, but are sometimes considered too heavy and noisy for their disabled wearers. Lightweight and quiet pie ...