Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Numerical Simulation of Rocket Exhaust Interaction with Lunar Soil

    SBC: CFD Research Corporation            Topic: T602

    Rocket plume impingement can cause significant damage and contaminate co-landing spacecraft and surrounding habitat structures during lunar landing operations. CFDRC and the University of Florida will develop an innovative simulation system for predicting surface erosion and debris transport caused by lunar surface rocket plume impingement. This simulation system combines 1) a unified continuum-ra ...

    STTR Phase II 2008 National Aeronautics and Space Administration
  2. Automation of Analysis Model Creation

    SBC: Technosoft, Inc            Topic: N06T018

    Although numerical analysis applications have proven to be effective and reasonably accurate, the effort required to develop the associated analysis models remains a challenging and time consuming task. While many meshing tools are currently available, decomposing and manipulating the design geometry and enhancing the topology for mesh construction are manual processes and place the heaviest dema ...

    STTR Phase II 2008 Department of DefenseNavy
  3. An On-Chip Nano-Plasmonics Based Urine Protein Assay Cartridge

    SBC: CFD Research Corporation            Topic: T302

    Long-term exposure to microgravity and radiation during space exploration can pose a critical threat to the health of a flight crew. Real-time monitoring of urine protein levels is an effective way to follow the onset and progress of many diseases and guide the prompt selection of proper therapy. The success of such diagnostic tasks, which is strongly desired for flight missions, critically depend ...

    STTR Phase I 2008 National Aeronautics and Space Administration
  4. Fuel/Oxidizer Injector Modeling in Sub- and Super-Critical Regimes for Deep Throttling Cryogenic Engines

    SBC: CFD Research Corporation            Topic: T802

    Accurate CFD modeling of fuel/oxidizer injection and combustion is needed to design and analyze liquid rocket engines. Currently, however, there is no mature modeling capability for liquid fuel/oxidizer injectors in LOCI-Chem, used by NASA and its contractors to analyze rocket engines. In this STTR, an innovative, high fidelity injection module will be developed that features the Level Set (LS) i ...

    STTR Phase I 2008 National Aeronautics and Space Administration
  5. Ultraviolet Light Devices for Vitamin D

    SBC: APOLLO LIGHT SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Vitamin D deficiency is now recognized as a significant health problem for middle-aged and older adults. Vitamin D deficiency exacerbates osteoporosis and causes the bone disease, osteomalacia. Vitamin D deficiency increases risk of skeletal fractures. It is well known that the ultraviolet B portion of the solar spectrum is responsible for the cutaneous product ...

    STTR Phase I 2003 Department of Health and Human Services
  6. PPMP as a Ceramide Catabolism Inhibitor for Chemotherapy

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goal is to develop 1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP) as a clinical inhibitor of ceremide catabolism, in order to enhance the anti-cancer activity of the cytotoxic retinoid, fenretinide (4-HPR). We have reported that 4-HPR increased ceramide in numerous pediatric and adult solid cancer and leukemia cell lines in vitro. We have also ...

    STTR Phase I 2003 Department of Health and Human Services
  7. Whole Mouse Cryo-Imaging

    SBC: BIOINVISION INC.            Topic: N/A

    DESCRIPTION (provided by applicant): BioInVision, Inc. and Case Western Reserve University researchers will develop a cryo-imaging system for 3D imaging of mice. It will serve very many applications in biological research and the biotechnology industry, in cluding mouse anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, pathogen/immune system response, and stem cells/regene ...

    STTR Phase II 2008 Department of Health and Human Services
  8. Minimally-Invasive Image-Guided Therapy for Cancer Treatment

    SBC: CONTRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a technology and eventually a minimally-invasive commercial system for image-guided photodynamic therapy for cancer. This is certainly in keeping with NCI's focus o n imaging in vivo for cancer screening, diagnosis, progression, image-guide therapy, treatment monitoring, and recurrence. In studies conducted ...

    STTR Phase I 2008 Department of Health and Human Services
  9. LifeBelt CPR: Combined Thoracic and Sternal Compression

    SBC: Deca-Medics            Topic: N/A

    N/A

    STTR Phase I 2003 Department of Health and Human Services
  10. Delivery system development for a reservoir targeted Lyme disease vaccine

    SBC: FoodSource Lure Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The incidence and geographic distribution of Lyme disease in the U.S. has increased steadily since its first description in 1977. Efforts to stem the spread of the disease through controlling the population of its tick vector and/or the mouse reservoirs of the disease have met with only limited success. The only approved human vaccine to protect against Lyme d ...

    STTR Phase I 2008 Department of Health and Human Services
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