Award Data

Hematopoiesis, the regulated production of mature blood cells, is a complex scheme of multilineage differentiation which occurs mainly in the bone marrow of adult mammals. Mature cells are continuously produced from progenitor (or precursor) cells. Consequently, assays which detect these progenitor cells are vital in many research and clinical settings. The current assay procedures suffer from a n ...

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The objective of this project is to develop a system for the optimized viewing of medical x-ray film. Illuminators currently used to view radiographs have a fixed-area, spatially uniform light output. This allows extraneous light to degrade visual performance and limits the viewable film density range to the dynamic range of the eye at a given adaptation level. The proposed viewing system will pro ...

END-STAGE RENAL FAILURE IS TREATED BY AN EXTRACORPOREAL DIALYSIS DEVICE. OVER 250,000 PATIENTS WORLDWIDE ARE MAINTAINED BY SUCH THRICE WEEKLY TREATMENTS. THE EVOLUTION OF THE MODERN DIALYZER HAS BEEN GREATLY DEPENDENT ON ADVANCES MADE IN POLYMERIC MATERIAL SCIENCE. WHILE THE MODERN DIALYSIS UNIT HAS REACHED A HIGH STATE OF SAFETY AND EFFICIENCY, THERE IS STILL ROOM FOR IMPROVEMENTS IN THE AREAS OF ...

PRINCIPAL INVESTIGATOR: Chi, Kefung AWARDEE ORGANIZATION: BioKwitech, Inc. 4204-L Sorrento Valley Boulevard San Diego, CA 92121 TELEPHONE NUMBER: (619) 587-6738 AWARDEE NUMBER: 200-93-0667 Cholera is a very severe epidemic disease caused by cholera toxin (CT) of Vibrio cholerae (V. cholerae). Two major serotypes (Ogawa and Inaba) have been identified as defined by O antigens of lipopolysaccharide ...

PRINCIPAL INVESTIGATOR: Nakano, Eileen T. AWARDEE ORGANIZATION: Hawaii Biotechnology group, Inc. 99-193 Aiea Heights Dr. Aiea, HI 96701 TELEPHONE NUMBER: (808) 486-5333 AWARDEE NUMBER: 200-93-0668 The incidence of measles infections in North America has recently increased. Sequence comparison between new wild-type isolates and the vaccine strain (Moraten) show distinct genetic variation, which may ...

PRINCIPAL INVESTIGATOR: Slack, John H. AWARDEE ORGANIZATION: Integrated Biotechnology Corp. 11711 North College Ave., Suite 196 Carmel, IN 46032 TELEPHONE NUMBER: (317) 575-7250 AWARDEE NUMBER: 200-93-0669 Measles virus, a severe acute highly contagious human pathogen, is not only responsible for clinical measles, but also for persistent central nervous system disease. In the United States, with t ...

Latex rubber articles in the form of condoms and gloves are used as barriers against the transmission of infectious diseases. The medical community have identified the use of condoms as an effective means for preventing the transmission of the human immunodeficiency virus (HIV) and other sexually transmitted diseases. Universal precaution procedures for health care workers requires wearing, and ch ...

PRINCIPAL INVESTIGATOR: Levin, Andrew E. AWARDEE ORGANIZATION: Immunetics 380 Green Street Cambridge, MA 02139 TELEPHONE NUMBER: (617) 492-5416 AWARDEE NUMBER: 200-93-0666 The research program is aimed at providing a simple and reliable serological test which can be used in clinical laboratories, physicians' offices and field stations as an aid in the rapid diagnosis of Lyme Disease. The test is b ...

PRINCIPAL INVESTIGATOR: Reynolds, Steven H. AWARDEE ORGANIZATION: Life Sciences, Inc. 2900 72nd Street, North St. Petersburg, FL 33710 TELEPHONE NUMBER: (813) 345-9371 AWARDEE NUMBER: 200-93-0680 Tuberculosis is reemerging as a health threat in the United States. Primary reasons include the susceptibility of HIV-infected persons, the lack of rapid and effective diagnostic tests, and recent outbrea ...