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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Continuous measurement of cell growth as an optimal tool in drug toxicity testing (Supplement)
SBC: EnTox Sciences LLC Topic: NCATSDESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IRE1 alpha inhibitors for Retinal Degenerative Diseases
SBC: Optikira, LLC Topic: NDESCRIPTION provided by applicant Approximately Americans suffer from vision loss due to Retinitis Pigmentosa RP Despite significant progress in elucidating the molecular genetics of RP over the past three decades no disease modifying therapies have been approved There is compelling evidence implicating endoplasmic reticulum ER stress in the pathogenesis of various forms of RP e ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Custom Fit 3D-Printed Pediatric Respiratory Masks
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NICHDDESCRIPTION provided by applicant This project will develop an FDA approved process D printing system and advanced D printable material suitable for point of care manufacturing of custom fit continuous positive airway pressure CPAP masks for neonates In extremely low birth weight infants nasal CPAP therapy is delivered via soft biocompatible neonatal sized nasal masks suitable for lon ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IRE1 alpha inhibitors for type 2 diabetes
SBC: Optikira, LLC Topic: 200DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Distance Filtering System for Retinal Implants
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
STTR Phase I: Mechanical Surface Treatment for High Performance Biodegradable Implants
SBC: SURFACE INTEGRITY, LLC Topic: BMThe broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...
STTR Phase I 2015 National Science Foundation -
Macromolecule Crystallization Screening Results Analysis
SBC: iXpressGenes, Inc. Topic: 100DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Serious STEM Games To Educate Middle School Students
SBC: MEADOWLARK SCIENCE AND EDUCATION, LLC Topic: ODDESCRIPTION provided by applicant Improving STEM focused curriculum is a primary objective of the current U S administration and is crucial for ensuring that upcoming generations receive the training and skills necessary to compete in the existing global economy To that end there is an urgent need for additional effective teaching tools able to reach a generation that requires instant access ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Therapeutic Approach for Cryptococcal Meningitis
SBC: Minnetronix Medical, Inc. Topic: NIAIDDESCRIPTION provided by applicant When Cryptococcus is manifested as Cryptococcal meningitis CM it creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treat There are now US cases and over million cases of CM worldwide annually with estimated deaths of per year CM is caused when Cryptococcus neoformans a basidiomyce ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health