You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Continuous measurement of cell growth as an optimal tool in drug toxicity testing (Supplement)
SBC: EnTox Sciences LLC Topic: NCATSDESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IRE1 alpha inhibitors for Retinal Degenerative Diseases
SBC: Optikira, LLC Topic: NDESCRIPTION provided by applicant Approximately Americans suffer from vision loss due to Retinitis Pigmentosa RP Despite significant progress in elucidating the molecular genetics of RP over the past three decades no disease modifying therapies have been approved There is compelling evidence implicating endoplasmic reticulum ER stress in the pathogenesis of various forms of RP e ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IRE1 alpha inhibitors for type 2 diabetes
SBC: Optikira, LLC Topic: 200DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Implantation of Bioengineered Intrinsically Innervated Internal Anal Sphincter (BioSphincter) to Treat Fecal Incontinence
SBC: CELLF-BIO LLC Topic: 300DESCRIPTION provided by applicant We propose to bring to market a novel regenerative medicine based therapy for fecal incontinence FI FI is the recurrent uncontrolled passage of fecal material The Internal Anal Sphincter IAS is responsible for maintaining anorectal continence Function of the IAS is dependent upon the neuromuscular integrity of both the smooth muscle and the intrinsic en ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of Small Molecules that Enhance the Delivery and the Pharmacological Effects of Oligonucleotides
SBC: Initos Pharmaceuticals LLC Topic: 999DESCRIPTION provided by applicant Antisense and siRNA oligonucleotides offer the promise of highly precise manipulation of genes involved in disease pathogenesis However despite the investment of enormous resources that promise has been fulfilled to only a limited degree A key impediment to oligonucleotide based therapeutics is the difficulty in delivering these large highly polar molecule ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Developing therapeutic inhibitors of CIB1 for breast cancer
SBC: Reveris Therapeutics Topic: 102DESCRIPTIONprovided by applicantBreast cancer is the most common malignancy in women living in the USwith more thannew cases diagnosed each yearand an estimatedwomen dying from the disease inGreater thanof these diagnoses are classified as triple negative breast cancerTNBCwhich is considered among the most aggressive breast cancer sub typeswith the worst prognosisTNBC is difficult to treat because ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
STTR Phase I: Ultrasonic Nanocoining for Creating Large, Low-Cost Arrays of Sub-Wavelength Features
SBC: SMART MATERIAL SOLUTIONS INC Topic: MNThe broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase 1 project is to drastically reduce the cost of creating large surfaces coated with functional nano-scale features. One example is the moth-eye structure, consisting of a continuous pattern of 200 nm wide by 200 nm tall features, that gives surface anti-reflective properties. An anti-reflective surface c ...
STTR Phase I 2015 National Science Foundation -
STTR Phase I: Mechanical Surface Treatment for High Performance Biodegradable Implants
SBC: SURFACE INTEGRITY, LLC Topic: BMThe broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...
STTR Phase I 2015 National Science Foundation -
Macromolecule Crystallization Screening Results Analysis
SBC: iXpressGenes, Inc. Topic: 100DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Serious STEM Games To Educate Middle School Students
SBC: MEADOWLARK SCIENCE AND EDUCATION, LLC Topic: ODDESCRIPTION provided by applicant Improving STEM focused curriculum is a primary objective of the current U S administration and is crucial for ensuring that upcoming generations receive the training and skills necessary to compete in the existing global economy To that end there is an urgent need for additional effective teaching tools able to reach a generation that requires instant access ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health