Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Corneal Endothelial Stem Cells for Treatment of Corneal Endothelial Dystrophies

    SBC: RASHMIVU LLC            Topic: N

    DESCRIPTION provided by applicant Corneal clouding caused by failure of the corneal endothelial deturgesence mechanism affects over million people in the US and well over million people worldwide It is the most common corneal disease and is historically a common cause of blindness Surgical treatment by corneal grafting has been successful when available but is limited by the availabili ...

    STTR Phase I 2014 Department of Health and Human Services
  2. IRE1 alpha inhibitors for Retinal Degenerative Diseases

    SBC: Optikira, LLC            Topic: N

    DESCRIPTION provided by applicant Approximately Americans suffer from vision loss due to Retinitis Pigmentosa RP Despite significant progress in elucidating the molecular genetics of RP over the past three decades no disease modifying therapies have been approved There is compelling evidence implicating endoplasmic reticulum ER stress in the pathogenesis of various forms of RP e ...

    STTR Phase I 2015 Department of Health and Human Services
  3. STTR Phase II: Nanofiber Fabrication via Melt Coextrusion for Fuel Filter Membranes

    SBC: POLYMERPLUS LLC            Topic: MN

    The broader impact/commercial potential of this Small Business Technology Transfer Phase II project is to demonstrate a low cost, environmentally friendly co-extrusion fabrication method for producing high surface area micro- and nanofiber based nonwoven fuel filter sheets. The micro-/nanofiber nonwoven structures are fabricated from two different hydrophilic and hydrophobic polymers in a melt co- ...

    STTR Phase II 2015 National Science Foundation
  4. STTR Phase II: Digital eWriter for The Classroom

    SBC: KENT DISPLAYS, INC.            Topic: AS

    This Small Business Technology Transfer (STTR) Phase II project develops eWriter devices for classroom use as a sustainable paper replacement technology and an effective tool for student-teacher interaction. The eWriters provide a paper-like writing experience and electronically capture, store, and transfer handwritten text and images. For education, eWriters introduce a sustainable paper replacem ...

    STTR Phase II 2015 National Science Foundation
  5. IRE1 alpha inhibitors for type 2 diabetes

    SBC: Optikira, LLC            Topic: 200

    DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase I: Mechanical Surface Treatment for High Performance Biodegradable Implants

    SBC: SURFACE INTEGRITY, LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...

    STTR Phase I 2015 National Science Foundation
  7. Macromolecule Crystallization Screening Results Analysis

    SBC: IXPRESSGENES, INC.            Topic: 100

    DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Serious STEM Games To Educate Middle School Students

    SBC: MEADOWLARK SCIENCE AND EDUCATION, LLC            Topic: OD

    DESCRIPTION provided by applicant Improving STEM focused curriculum is a primary objective of the current U S administration and is crucial for ensuring that upcoming generations receive the training and skills necessary to compete in the existing global economy To that end there is an urgent need for additional effective teaching tools able to reach a generation that requires instant access ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. STTR Phase I: Advanced Manufacturing Processes for Multiple Field Freeform Microlens Arrays for Ultra-Low Cost Medical Endoscopy

    SBC: Ohio Surgical Optics, LLC            Topic: MN

    The broader impact/commercial potential of this Small Business Technology Transfer Research (STTR) Phase I project is that smaller and less expensive medical endoscopes will be made possible, which will allow physicians to see better inside the human body. These devices will shorten recovery times, improve diagnosis and treatment, move procedures from operating rooms to exam rooms, and lower healt ...

    STTR Phase I 2015 National Science Foundation
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