Award Data

Limb loss affects approximately 1.9 million people in the United States. It is well established that lower-limb amputees show greater metabolic demands during gait and more limited mobility compared to non-disabled individuals. Currently, there is no lower-extremity prosthesis available that can monitor the metabolic costs of the amputee. The proposed solution, code-named TEQUILA (Total Energy exp ...

In this project, Parabon NanoLabs will employ its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce artificial vaccines against the biothreat agent ricin on DNA origami decorated first with natural epitopes and ultimately with artificial epitotopes (hereafter"mimotope") constructed from a predefined set of ...

Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

The TORC team, which includes Dr. Jonathan Sprinkle of the University of Arizona (UA), will develop enabling software and modeling methods for the Autonomous System Demonstration and Experimentation Workbench. The workbench will assist test engineers, systems engineers and analysts in designing and equipping autonomous unmanned vehicles for a variety of operations. The proposed work is based on o ...

MATSYS proposes to develop reactive materials compositions and processing techniques for structural reactive composites for blast enhancement. This effort will combine our unique expertise in instrumented-Hot Isostatic Pressing (HIP) with new approaches in reactive materials design to develop a new generation of cost-efficient and highly reactive materials. The proposed material system will use ...

The Army Defense Health Program has a need for a novel freestanding device to sample and collect a broad spectrum of adult flying insects for the purpose of analyzing possible disease vectors. McQ proposes to develop a flying insect sampling device (FISDe) that utilizes a modular approach to allow the assembly of components necessary for the survey mission. This device will allow for the automat ...

Flying insect vectors and the diseases they transmit continue to be a significant source of concern for United States service members deployed in field operations. In an effort to reduce contact between the vectors and humans, military entomologists are often required to perform surveillance to assess the prevalence of disease vectors and to evaluate the effectiveness of control measures. Survei ...

Military personnel and first responders must be prepared to operate under the threat of a wide range of CBRNE threats (chemical, biological, radiological, nuclear, and high explosive) and rapidly counter WMD hazards. Daily-wear uniforms such as the army combat uniform (ACU) or the CWU-27/P flight suit are breathable and lightweight and provide basic abrasion and fire protection, but are not capab ...

Use of information technology within the U.S. healthcare system has made considerable strides forward in the past few years but to fully realize the full benefits of an Electronic Health Record - including higher quality and safety of care through access to the patient"s complete health record at the point of care, increased participation by patients in their healthcare through access to a shared ...

For applications in DoD satellite systems, devices based on novel nanomaterials offer significant advantages over traditional technologies in terms of light-weight and efficiency. Examples of such novel devices include quantum dot (QD) based solar cells, photodetectors, radars and sensors. However, the response of these devices to radiation effects is not well understood, and radiation effects mod ...