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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Handheld IR Raman Spectroscopy for Rapid Chemical Identification

    SBC: Aerius Photonics, LLC.            Topic: CBD08102

    In Phase I, Aerius Photonics demonstrated Raman spectroscopy at 785 nm, 980 nm, and 1064 nm, with only 1064 nm-based excitation showing a reduction in fluorescence. In addition, Aerius Photonics and partner Ahura Scientific, demonstrated a breadboard version of an InGaAs-based Raman spectrometer to assess any engineering challenges. By the end of a Phase III, Aerius proposes to develop a handheld ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. Novel MicroPower Source for Insect Based Sensor and Communication Platforms

    SBC: CFD RESEARCH CORPORATION            Topic: CBD09105

    Our objective is to develop a novel micropower source to be integrated with a microsensor, and communication chip on an insect, delivering a state-of-the-art unmanned chemical detection device. The biological fuel cell (Bio-FC) power source will leverage ongoing research at CFDRC and provide a compact/lightweight power supply for mounting on numerous types of insects and producing necessary power ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: GUILD ASSOCIATES INC            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. Durable Anti-fog Coatings for Contoured Plastic Substrates Using Nanoparticles with Tunable Size and Surface Chemistry

    SBC: INNOSENSE CORPORATION            Topic: CBD09101

    Currently fielded respiratory protective systems in the Joint Services General Purpose Mask (JSGPM) program degrade in visual performance capability in extreme hot and cold environments. Optical and mechanical properties of existing anti-fog coatings also diminish when subjected to cleaning/sanitization operations. To address these needs, InnoSense LLC (ISL), in Phase I, has combined nanomaterials ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. An Enhanced Quarter-Sized Optical NEMS Based Methyl Salicylate Sensor System (MS3)

    SBC: IMAGINATIVE TECHNOLOGIES, LLC            Topic: CBD09103

    Building on our successful Phase I work our Phase II objectives are to complete development and integration of our two proposed sensors into an unprecedented self-confirming MeS detection system further refining our ability to meet key requirements identified in Phase I. More specifically, we will develop a NEMS based MeS sensor system complete with a telemetry system and/or a remote logging, data ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. CBRN Sensor and Sensor Netting Algorithms

    SBC: NUMERICA CORPORATION            Topic: CBD09110

    Coordination and merging of multiple distributed sensors over a communications network can substantially improve estimates of the type and severity of potential hazards for command and control (C2) decision makers. These sensors include long range instruments such as radar, infrared (IR), electro-optical, and long wave hyper spectral; short range instruments such as Raman spectrometers; and a wid ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device

    SBC: Physical Optics Corporation            Topic: CBD10102

    To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to develop a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses in-house developed mature compone ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  10. Miniature Residual Life Indicator

    SBC: Physical Optics Corporation            Topic: CBD10106

    Impregnated ASZM-TEDA carbon employed as highly adsorptive materials in Collective Protection (ColPro) systems loses the ability to adsorb toxic chemicals because of exposure to temperature, humidity, battlefield contaminants, and other pollutants. To address the Chemical and Biological Defense (CBD) need for a residual life indicator (RLI) capable of probing the degradation in physical adsorption ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
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