You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Mycotoxin Neutralization Treatment

    SBC: Physical Optics Corporation            Topic: CBD152003

    To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Mycotoxin Adsorption with Hemocompatible Porous Polymer Beads

    SBC: CytoSorbents Medical Inc.            Topic: CBD152003

    Acute exposure to mycotoxins can lead to systemic toxicity and even death. With no specific treatment available, aflatoxin and trichothecene T-2toxin, in particular, are of concern as potential biological weapons due to their toxicity, thermal and UV stability and easy accessibility. As amedical countermeasure, we propose the development of highly porous polymer beads optimized for removal of afla ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  3. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD Research Corporation            Topic: CBD152003

    Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  4. Plasmid-seeded aligned nanofibrillar scaffold for acute muscle injury treatment

    SBC: Fibralign Corporation            Topic: DHP14009

    Based on encouraging Phase I feasibility results, we propose developing a novel gene therapy approach to promote guided vascular regeneration in treating extremities after traumatic injury. Our approach is to provide thread-like implants comprised of aligned nanofibrillar collagen scaffolds loaded with Hepatocyte Growth Factor (HGF) vectors (e.g., HGF DNA plasmid, modified mRNA) designed to enhanc ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  5. Use of Highly Porous Polymer Beads to Remove Anti-A and Anti-B Antibodies from Plasma for Transfusion

    SBC: CytoSorbents Medical Inc.            Topic: DHP15B001

    The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is rel

    SBIR Phase I 2016 Department of DefenseDefense Health Program
  6. Smart Femtosecond Fiber Laser Wound Healing System

    SBC: POLARONYX, INC.            Topic: DHP15B002

    Based on our success in developing the world first commercial high energy femtosecond fiber laser system and our leading proprietary technology development in ultrashort pulsed fiber laser material processing, PolarOnyx proposes, for the first time, a compact high energy fiber laser based smart wound healing tool to meet with the requirement of this DHP solicitation. It includes a high energy fs f ...

    SBIR Phase I 2016 Department of DefenseDefense Health Program
  7. High Fidelity Computational Models for Aggregated Tissue Interaction in Surgical Simulations

    SBC: CFD Research Corporation            Topic: DHP16A001

    Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

    STTR Phase I 2016 Department of DefenseDefense Health Program
  8. Adjustable Focus Lenses for Respiratory Protection

    SBC: VOXTEL, INC.            Topic: CBD152001

    A low-cost, adjustable optical-correction technology will be developed for integration with AVON M50 respiratory protective masks, allowing forfast, adjustable vision correction. Variable-focus lenses will be designed using 3D freeform gradient index materials, which allow both opticalpower and geometric and chromatic aberrations corrections to be achieved in planar films. A Phase I prototype will ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  10. Wavelet-Based Approach for Signal Processing and Analysis

    SBC: Physical Optics Corporation            Topic: CBD152006

    To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
US Flag An Official Website of the United States Government