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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A research and drug development tool for the real time in vitro study of single c

    SBC: KYTARO, INC.            Topic: 100

    DESCRIPTION In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor ligand interactions in real time This tool finds critical applications in research and drug development and would allow researchers to study and manipulate adhesion by bioactive compounds to promote or inhibit physiological processes There is a ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Self-Sealing Therapy Ostomy Pouch

    SBC: Korosensor.Com, Inc.            Topic: 300

    DESCRIPTION provided by applicant Eden Medical proposes to develop a Self Sealing Therapy Ostomy Pouch S TOP to stop leakage that leads to skin breakdown and trauma for ostomy care patients The S TOP will detect leakage inform the patient and prevent leakage occurrence providing better patient comfort and well being and eliminating the cycle of misery due to an ineffective seal and skin br ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Tools for Distance Delivery of an Evidence-based AD Family Caregiver Intervention

    SBC: HEALTHCARE INTERACTIVE, INC.            Topic: NIA

    DESCRIPTION provided by applicant As the US population ages Alzheimerandapos s disease and related disorders ADRD will present an emotional and financial burden to an increasing number of families and the U S healthcare system More than of the care for persons with ADRD is provided by family members at home who need ongoing support to manage the daunting physical and psychological demands of care ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Long-Acting G-CSF Analog for Treating ARS

    SBC: Bolder Biotechnology, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Return on Investment Tool for Effective Medical Training (RITE-MT)

    SBC: Design Interactive, Inc            Topic: OSD11H19

    The Return on Investment Tool for Effective Medical Training (RITE-MT) tool aims to substantially improve the decision making process of training system requirements and acquisition professionals by objectively quantifying training system Return On Training Investment (ROTI) based on lifecycle cost, schedule and performance impacts. RITE-MT uses a training needs-based approach to ROTI which incorp ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  10. Remote Anger and Stress Management (M-SAT)

    SBC: Design Interactive, Inc            Topic: OSD11H13

    Concern has been raised over the prevalence of behavioral health disorders in military personnel returning from deployment to the Middle East. While not appearing as an overt physical injury, disruptions of a psychological nature are often as debilitating, and there is an increasing need for support tools. Such tools should allow for standardized tracking, monitoring, and mitigation of anger and ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
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