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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Cell-based Assay for Botulinum Neurotoxin Detection and Development

    SBC: Q-Track Corporation            Topic: NIEHS

    DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Activity of Fully Deleted Helper-Virus Independent Adenoviral Gene Therapy Vector

    SBC: ISOGENIS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Numerous diseases are caused by gene defects. The goal of gene therapy is the effective treatment or cure of these diseases by the introduction of the normal gene or repair of the gene defect. A large research effort has been mounted to optimize gene transfer vectors mostly based on adenoviruses and retroviruses. Yet, the initial promise of gene therapy has bee ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. A custom microchip amplifier for patch clamp electrophysiological recording

    SBC: MAINSTREAM ENGINEERING CORP            Topic: NIEHS

    DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. ADAPT: After Deployment Adaptive Parenting Tools

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this project is to strengthen family functioning and improve child outcomes in military families after deployment. To achieve this end, we will develop, evaluate, and disseminate ADAPT: After Deployment: Adaptive Parenting Tools, an online, interactive resource for military parents. Significance: ADAPT responds to the urgent parenting needs of veter ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. A Diarylheptanoid Scaffold to Treat Taopathies

    SBC: CFD RESEARCH CORPORATION            Topic: NIGMS

    DESCRIPTION: Pulmonary drug delivery is increasingly used for both treatment of lung diseases (such as asthma and chronic obstructive pulmonary disease) and in delivering drugs to the systemic circulation. To reach the desired effectiveness and safety oforally/nasally inhaled drugs, appropriate deposition of drugs on targeted region is essential. Due to complex pharmaceutical and physiological fa ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Aluminum Oxide Nanoparticles Conjugated to Antigens Potently Induce Tumor Specifi

    SBC: UBIVAC, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): PROJECT SUMMARY Although prophylactic vaccines have potential for prevention of high risk human papilloma virus (HPV) infection they have no therapeutic efficacy. It has been estimated that there will be no measurable decline of HPV- associated tumors before 2040 (Hellner et al., 2011). Likewise, other HPV-associated angogenital and head and neck cancers are pr ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. AMES+Brain Stimulation: Treatment for Profound Plegia in Stroke

    SBC: AMES TECHNOLOGY, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): An estimated 30% of chronic stroke patients with motor disabilities of the limbs are plegic in the hand or the foot - that is, they cannot move the hand or foot. While some plegic stroke patients have completely paralyzed muscles, without the ability to activate even minimally the plegic muscles ( profound plegia ), other plegic stroke patients are capable of p ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. A Nanofluidic Nanoplasmonic Platform for Multiplexing Detection of Cancer Biomark

    SBC: CFD RESEARCH CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): This project aims to develop a novel nanofluidic-nanoplasmonic platform to realize multiplexed monitoring of biological binding processes, specifically for detection of cancer biomarkers in bio-fluids. In contrast to current large-sized, cumbersome surface plasmon resonance (SPR) sensing technology, the proposed device is comprised of a multilayer nanostructure ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. A noninvasive optical imaging of retinal amyloid beta deposits in AD patients

    SBC: Oregon Center For Applied Science, Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Marital discord is a significant risk factor for a range of negative mental and physical health outcomes.1, 2 Individuals in unhappy relationships experience increases in stress, anxiety, functional impairment, and depressive symptoms3 and are at significant risk for substance abuse disorders.4-7 Furthermore, work loss associated with marital problems translate ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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