Award Data

DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

Thermal Stir Welding (TSW) provides advancement over the more conventional Friction Stir Welding (C-FSW) process because it separates the primary processes variables thereby allowing independent control of metal stirring and forging from the stir zone temperature. However, the feedback for precise control of the stir zone temperature, and hence the process parameters to sustain that temperature wi ...

A spacecraft thermal control system must keep the vehicle, avionics and atmosphere (if crewed) within a defined temperature range. Since water is non-toxic and good for heat transport, it is typically used as the coolant that circulates within the crew cabin boundary. This loop then interfaces with another low freeze point fluid, such as ammonia, for transport of heat to a radiator where the tempe ...

Project involves development of new flexible FR polyurethane (PU)insulation foams through a non-toxic environmentally friendly composite approach. Foams have bound-in polymeric phosphonate FRs, with added synergists and smoke suppressants. Such foams will not leach FR. Foams have fine cell structure and excellent flexible foam properties. Cone performance of the identified foam family (368 peak ...

With the capacity and performance of FPGAs suitable for space borne applications continuously increasing, the design of FPGAs is becoming increasingly complex involving trading off or simultaneous optimization of space, speed, and power. RNET and ANL are proposing to develop software infrastructure that facilitates automatic performance tuning of FPGAs in terms of speed, power, and size. We introd ...

The liberation of particles induced by rocket plume flow from spacecraft landing on unprepared regolith of the Moon, Mars, and other destinations poses high mission risks for robotic and human exploration activities. This process occurs in a combination of "extreme environments" that combine low gravity, little or no atmosphere, with rocket exhaust gas flow that is supersonic and partially rarefie ...

The proposed solution exploits recent advances in computer vision to conceive of a single-camera + gyro + accelerometer vision-based navigation solution such that the processing will be lightweight (requiring only a single optical flow sample per frame). Known landmarks (natural or artificial) will have absolute positions known to planetary exploration worker robots. The worker robot can identif ...

Launch vehicles experience extreme acoustic loads during liftoff driven by the interaction of rocket plumes and plume-generated acoustic waves with ground structures. Currently employed predictive capabilities to model the complex turbulent plume physics are too dissipative to accurately resolve the propagation of acoustic waves throughout the launch environment. Higher fidelity liftoff acoustic a ...