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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Nublu: Assured Information Sharing in Clouds

    SBC: Modus Operandi, Inc.            Topic: AF11BT30

    ABSTRACT: We propose to develop an assured information sharing framework for cloud-based systems that leverages our ongoing work in the areas of policy-based usage management and semantic interoperability. The development of this framework will involve the creation of a novel approach to information sharing that treats security as a commodity that can be dynamically provisioned within the cloud, ...

    STTR Phase II 2013 Department of DefenseAir Force
  5. Design and Analysis of Multi-core Software

    SBC: SECURBORATION, INC.            Topic: OSD11T03

    Modern processor design is trending increasingly toward multicore architectures. This is problematic for programmers because writing a correct parallel program is known to be difficult compared to writing the equivalent sequential program. Additionally, a wide body of sequential code has already been developed that cannot exploit the power offered by these new cores because it was written in a s ...

    STTR Phase II 2013 Department of DefenseAir Force
  6. Autonomic Performance Assurance for Multi-Processor Supervisory Control

    SBC: COLORADO ENGINEERING INC.            Topic: OSD11T01

    Multi-processor computing systems are growing in capacity and usage. They encompass multiple, distributed implementations as well as heterogeneous, embedded computing architectures. The processing density enabled by such approaches holds promise for unmanned combat air vehicles (UCAVs) with their plethora of mission sensors and command and control processing requirements. However, the software ...

    STTR Phase II 2013 Department of DefenseAir Force
  7. Spatiotemporal Nonlinear Data Analysis Tools and Reduced Order Models for Prediction of High-Pressure Reacting Flow Dynamics and Control

    SBC: Spectral Energies, LLC            Topic: AF12BT15

    ABSTRACT: This Phase-I research effort is designed to forward the engineering investigation of the dynamics and control of turbulent combustion in high-pressure combustion systems by developing a set of game-changing nonlinear analysis tools that can significantly improve the post-processing speed and intelligent data mining of large numerical or experimental data sets. Moreover, a system based o ...

    STTR Phase I 2013 Department of DefenseAir Force
  8. Operating System Mechanisms for Many-Core Systems

    SBC: SECURBORATION, INC.            Topic: OSD11T04

    In the Phase I portion of this STTR, Securboration and renowned multicore expert Dr. Frank Mueller from North Carolina State University designed, developed, and benchmarked the proof-of-concept Pico-kernel Adaptive and Scalable Operating-system (PICASO) for many-core architectures. The Securboration Team took a scientific, experimentation-based approach to identifying and resolving shortcomings wi ...

    STTR Phase II 2013 Department of DefenseAir Force
  9. First-Principles-Based Framework for Discovery and Design of Sustainable Non-Rare-Earth High-Temperature Alloy Systems

    SBC: CFD Research Corporation            Topic: OSD12T06

    In this STTR Phase I project, CFD Research Corporation and University of Nebraska at Omaha will develop a preliminary computationally-driven first-principles framework for discovery and design of non-RE-containing alloys for high temperature applications. While rare-earth (RE) based alloys have played a pivotal role in modern defense and high-tech industry, sustainability of RE-based materials is ...

    STTR Phase I 2013 Department of DefenseAir Force
  10. Suppression of Wind Turbine Clutter from Radar Data

    SBC: Matrix Research, Inc.            Topic: AF12BT05

    ABSTRACT: It is well known that wind turbine clutter (WTC) presents a significant challenge to detecting targets in civilian and military applications. The large radar cross section (RCS) of wind turbines, combined with their significant range of Doppler spread, make traditional clutter mitigation techniques effectively useless. The objective of this Phase I effort is to develop a physically con ...

    STTR Phase I 2013 Department of DefenseAir Force
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