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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. On Demand Energy Activated Liquid Decontaminants and Cleaning Solutions

    SBC: TDA Research, Inc.            Topic: A12aT005

    Decontamination of chemical and biological threats demands a very reactive solution. It is ideal to generate the decontaminants on-site: the activated decontaminant is highly reactive and quickly destroys chemical and biological warfare agents; prior to activation the ingredients can be safely stored for years, shipped, and handled. TDA's electrochemical decontamination (eClO2) technology u ...

    STTR Phase II 2013 Department of DefenseArmy
  5. Solar Blind MgZnO Photodetectors

    SBC: AGNITRON TECHNOLOGY, INC            Topic: A13AT006

    This Phase I program is focused on enhancement of the performance of MgZnO based solar blind detectors. MgZnO alloys have superior optoelectronic properties with bandgaps suitable for solar blind detection. Issues related to doping and miscibility will be addressed. This will involve the use of advanced MOCVD and MBE growth techniques and consideration of both Schottky and p-n junction devices. No ...

    STTR Phase I 2013 Department of DefenseArmy
  6. Additive Manufacturing of Multifunctional Nanocomposites

    SBC: Sciperio, Inc.            Topic: A13AT010

    Sciperio with team members Georgia Institute of Technology and Centecorp have teamed up to develop an Additive Manufacturing Composite using nano and micro fillers. The team will develop multi-scale models that are supported by experimental characterization for advanced 3D Printable materials. Inelastic response of high strength hierarchical structures composed of engineered materials and specif ...

    STTR Phase I 2013 Department of DefenseArmy
  7. A universal framework for non-deteriorating time-domain numerical algorithms in Maxwell's electrodynamics

    SBC: COMPUTATIONAL SCIENCES LLC            Topic: A13AT008

    The project will remove a key difficulty that currently hampers many existing methods for computing unsteady electromagnetic waves on unbounded regions. Numerical accuracy and/or stability may deteriorate over long times due to the treatment of artificial outer boundaries. We propose to develop a universal algorithm and software that will correct this problem by employing the Huygens'principl ...

    STTR Phase I 2013 Department of DefenseArmy
  8. Low Cost Fabrication of Armor Protection Systems for Military Tactical Vehicles

    SBC: NexGen Composites LLC            Topic: A13AT021

    There is a great need and opportunity to develop lower cost manufacturing process for ceramic tile-based composite armor system for military tactical vehicles. The threat levels encountered by the military tactical vehicles, particularly due to the Improvised Explosive Devices (IED) pose an ever-increasing need for more lightweight and effective vehicle armor system at an affordable cost. A low-co ...

    STTR Phase I 2013 Department of DefenseArmy
  9. Soft and Elastomeric Intramuscular Electrode with Therapeutic Delivery Capability

    SBC: TDA Research, Inc.            Topic: A13AT019

    Approximately 5-6% of military injuries involve some form of major peripheral nerve injury with little chance of spontaneous healing. Currently these injuries lead to major impairment of voluntary muscle function in the limbs and extremities, making tasks of walking, reaching, grasping, etc. very difficult or impossible for many patients. It is not enough to focus therapeutic treatment on the se ...

    STTR Phase I 2013 Department of DefenseArmy
  10. HIGH STRENGTH AND TOUGHNESS TUNGSTEN CARBIDE (WC) WITH NON-COBALT (Co) MATRICES

    SBC: UES, Inc.            Topic: OSD12T07

    Cemented cobalt-tungsten carbide is a material with attractive properties including high hardness and fracture toughness that has found success in a wide variety of applications ranging from drilling bits to armor piercing projectiles. However, with the classification of cobalt as a strategic and critical material that the US Department of Health and Human Services has classified as"reasonably ant ...

    STTR Phase I 2013 Department of DefenseArmy
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